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  4. Hemopexin Protein, Cynomolgus (HEK293, His)

Hemopexin Protein, Cynomolgus (HEK293, His)

Cat. No.: HY-P701003
Handling Instructions

Hemopexin Protein binds to heme, transporting it to the liver for degradation and iron retrieval. After heme processing, Hemopexin returns to circulation, ready for another cycle of heme binding and transport. Hemopexin Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Hemopexin protein, expressed by HEK293 , with C-His labeled tag. The total length of Hemopexin Protein, Cynomolgus (HEK293, His) is 439 a.a., with molecular weight of 60-80 kDa.

For research use only. We do not sell to patients.

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Description

Hemopexin Protein binds to heme, transporting it to the liver for degradation and iron retrieval. After heme processing, Hemopexin returns to circulation, ready for another cycle of heme binding and transport. Hemopexin Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Hemopexin protein, expressed by HEK293 , with C-His labeled tag. The total length of Hemopexin Protein, Cynomolgus (HEK293, His) is 439 a.a., with molecular weight of 60-80 kDa.
Background

Hemopexin protein has the ability to bind to heme and facilitates its transportation to the liver for degradation and subsequent retrieval of iron. Once the heme is processed, the hemopexin molecule is released back into circulation, ready for another cycle of heme binding and transport.
Species

Cynomolgus
Source

HEK293
Tag

C-His
Accession

A0A2K5WVL1 (N24-Y462)
Gene ID

102133434  [NCBI]
Molecular Construction
N-term
Hemopexin (N24-Y462)
Accession # A0A2K5WVL1
His
C-term
Synonyms
Hemopexin; Hpx; Hpxn
Molecular Weight

60-80 kDa
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

Hemopexin Protein, Cynomolgus (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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