Hemopexin Protein, Cynomolgus (HEK293, His)

Hemopexin Protein binds to heme, transporting it to the liver for degradation and iron retrieval. After heme processing, Hemopexin returns to circulation, ready for another cycle of heme binding and transport. Hemopexin Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Hemopexin protein, expressed by HEK293 , with C-His labeled tag.

For research use only. We do not sell to patients.
  • Species: Cynomolgus
  • Source: HEK293
  • Storage:
    Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
  • Biological Activity
  • Technical Parameters
  • Product Properties
  • Documentation
  • Help & FAQs

Biological Activity

Description

Hemopexin Protein binds to heme, transporting it to the liver for degradation and iron retrieval. After heme processing, Hemopexin returns to circulation, ready for another cycle of heme binding and transport. Hemopexin Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Hemopexin protein, expressed by HEK293 , with C-His labeled tag.

Background

Hemopexin protein has the ability to bind to heme and facilitates its transportation to the liver for degradation and subsequent retrieval of iron. Once the heme is processed, the hemopexin molecule is released back into circulation, ready for another cycle of heme binding and transport.

Technical Parameters

  • Species Cynomolgus
  • Source HEK293
  • Tag C-8*His
  • Accession
  • Gene ID
  • Molecular Construction
    • N-term
    • Hemopexin (N24-Y462)
      Accession # A0A2K5WVL1
    • 8*His
    • C-term
  • Protein Length

    Full Length of Mature Protein

  • Synonyms

    HPX; Epididymis Secretory Sperm Binding Protein; Hemopexin; HX; Beta-1B-Glycoprotein

  • AA Sequence

    NPLPPTSAHGNVAEGETKPDPDVTERCSDGWSFDATTLDDNGTMLFFKGEFVWKSHKWARELISETWKNFTSPVDAAFRHGHQSVFLIKGDKVWVYPPEKKEKGYPKLLQDKFPGIPSPLDAAVECHRGECQAEGILFFQGDHKWFWDLATGTMKKRYWSAVGNCSSALRWLGRYYCFQGNQFLRFNPVTGEVPPRYPLDVRDYFMPCPGRGHGHRNGTGHGNGTHHGPEYMRCSPHLVLSALMSDNHGATYAFSGTHYWRLDTSRDGWHSWPIAHQWPQGPSTVDAAFSWEEKLYLVQGTQVYVFLTKGGYTLVSGYPKRLEKEVGSPHGIILDSVDAAFVCPGSSRLHIMAGRRLWWLDLKSGAQATWTELPWPHEKVDGALCVEKSLGPNSCSANGPGLYLIHGPNLYCYSDVEKLNAAKSPPQPQKVTSLLGCTY

  • Predicted Molecular Mass

    50.3 kDa

  • Molecular Weight

    Approximately 60-80 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

  • Glycosylation

    Yes

  • Purity

    ≥ 95%, as determined by reducing SDS-PAGE.

Product Properties

Appearance

Solution

Endotoxin Level

<1 EU/μg, determined by LAL method.

Storage & Stability

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Calculators

Reconstitution Calculator

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) Volume (to add to vial)
=
Mass (in vial) Mass (in vial)
÷
Desired Reconstitution Concentration Desired Reconstitution Concentration
Dilution Calculator

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

Concentration (start) Concentration (start)
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The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
Unit/mg
= 106 ÷
Biological Activity (ED50) Biological Activity (ED50)
106 ÷
ng/mL
MOQ
Minimum order quantity
100 mg

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