2. Recombinant Proteins
  3. Fc Receptors
  4. Immunoglobulin Fc Region
  5. IgG2C
  6. IgG2C Fc Protein, Mouse (HEK293)

IgG2C Fc Protein, Mouse (HEK293)

Cat. No.: HY-P700737
Handling Instructions

IgG2C Fc is a subclass of IgG2. Mouse IgG2c Fc loop residues have stronger receptor binding affinity than mouse IgG2b or human IgG1. IgG2C Fc Protein, Mouse (HEK293) is the recombinant mouse-derived IgG2C Fc protein, expressed by HEK293 , with tag free. The total length of IgG2C Fc Protein, Mouse (HEK293) is 234 a.a., with molecular weight of 30-40 kDa.

For research use only. We do not sell to patients.

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Description

IgG2C Fc is a subclass of IgG2. Mouse IgG2c Fc loop residues have stronger receptor binding affinity than mouse IgG2b or human IgG1. IgG2C Fc Protein, Mouse (HEK293) is the recombinant mouse-derived IgG2C Fc protein, expressed by HEK293 , with tag free. The total length of IgG2C Fc Protein, Mouse (HEK293) is 234 a.a., with molecular weight of 30-40 kDa.
Background

Antibodies protect pathogens and diseased tissues from invasion through several different mechanisms, including neutralization, antibody-dependent cell-mediated cytotoxicity (ADCC), complement-mediated cytotoxicity, phagocytosis, and phagocytosis. The mouse strains expressed three IgG2 subclasses: IgG2a, 2b and 2c. Mouse IgG2c Fc ring residues promote stronger receptor-binding affinity than mouse IgG2b or human IgG1[1].
Species

Mouse
Source

HEK293
Tag

Tag Free
Accession

F6TQW2 (I97-S330)
Gene ID

/
Molecular Construction
N-term
IgG2C Fc (I97-S330)
Accession # F6TQW2
C-term
Synonyms
Ighg2c; IgG2C
Molecular Weight

30-40 kDa
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

IgG2C Fc Protein, Mouse (HEK293) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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