KCNJ2 Protein, Human (HEK293, His, MBP, Flag)
KCNJ2 Protein, Human (HEK293, His, MBP, Flag) is the recombinant human-derived KCNJ2, expressed by HEK293 , with His, MBP, Flag labeled tag. ,
- Species: Human
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
KCNJ2 Protein, Human (HEK293, His, MBP, Flag) is the recombinant human-derived KCNJ2, expressed by HEK293 , with His, MBP, Flag labeled tag. ,
Background
KCNJ2 encodes inward rectifier potassium channels that preferentially allow potassium influx into the cell. Their voltage dependence is regulated by extracellular potassium concentration, with higher concentrations shifting the activation range toward more positive potentials. The inward rectification primarily results from blockage of outward current by intracellular magnesium. These channels can be blocked by extracellular barium or cesium and likely contribute to action potential waveform and excitability in neuronal and muscle tissues. by similar: These properties have been consistently observed across multiple studies.
Technical Parameters
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Species Human
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Source HEK293
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Tag His;MBP;Flag
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Accession
P63252 (M1-I427)
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Gene ID3759
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Protein Length
Full Length
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Synonyms
KCNJ2; Potassium Channel, Inwardly Rectifying Subfamily J, Member 2; Potassium Inwardly Rectifying Channel Subfamily J Member 2; Potassium Channel, Inwardly Rectifying Subfamily J Member 2; IRK1; Potassium Voltage-Gated Channel Subfamily J Member 2; Kir2.
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AA Sequence
MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARDLAEKKYILSNANSFCYENEVALTSKEEDDSENGVPESTSTDTPPDIDLHNQASVPLEPRPLRRESEI
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Predicted Molecular Mass
92.1 kDa
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Purity
≥ 80%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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