LMW-PTP/ACP1 Protein, Human (GST)
LMW-PTP/ACP1, a phosphatase, acts on tyrosine phosphorylated proteins, low-molecular-weight aryl phosphates, and natural and synthetic acyl phosphates. Notably, there are substrate specificity differences between isoform 1 and isoform 2, with isoform 2 lacking phosphatase activity. LMW-PTP/ACP1 Protein, Human (GST) is the recombinant human-derived LMW-PTP/ACP1 protein, expressed by E. coli , with N-GST labeled tag.
- Species: Human
- Source: E. coli
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
LMW-PTP/ACP1, a phosphatase, acts on tyrosine phosphorylated proteins, low-molecular-weight aryl phosphates, and natural and synthetic acyl phosphates. Notably, there are substrate specificity differences between isoform 1 and isoform 2, with isoform 2 lacking phosphatase activity. LMW-PTP/ACP1 Protein, Human (GST) is the recombinant human-derived LMW-PTP/ACP1 protein, expressed by E. coli , with N-GST labeled tag.
Background
LMW-PTP (Low Molecular Weight Protein Tyrosine Phosphatase), also known as ACP1, functions as a phosphatase acting on tyrosine phosphorylated proteins, low-molecular-weight aryl phosphates, and both natural and synthetic acyl phosphates. Notably, there are differences in substrate specificity between isoform 1 and isoform 2. It's important to highlight that isoform 2 does not possess phosphatase activity.
Technical Parameters
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Species Human
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Source E. coli
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Tag N-GST
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Accession
AAI06012.1 (M1-H158)
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Molecular Construction
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N-term
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GST
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ACP1 (M1-H158)
Accession # P24666 -
C-term
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Protein Length
Full Length
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Synonyms
ACP1; Red Cell Acid Phosphatase 1; Acid Phosphatase 1; Adipocyte Acid Phosphatase; LMW-PTP; LMW-PTPase; Low Molecular Weight Phosphotyrosine Protein Phosphatase; Cytoplasmic Phosphotyrosyl Protein Phosphatase; LMWPTP; Protein-Tyrosine-Phosphatase, Isoform
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AA Sequence
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNRVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
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Predicted Molecular Mass
44.3 kDa
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Molecular Weight
Approximately 40 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 85%, as determined by reducing SDS-PAGE.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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