2. Recombinant Proteins
  3. CD Antigens
  4. Epithelial cell CD Proteins
  5. CD228
  6. Melanotransferrin/CD228 Protein, Mouse (HEK293, Fc)

Melanotransferrin/CD228 Protein, Mouse (HEK293, Fc)

Cat. No.: HY-P76495
Handling Instructions

Melanotransferrin/CD228 protein is involved in cellular iron uptake, undergoing internalization and recycling to the cell membrane. Each subunit binds a single iron atom, suggesting a role in intracellular iron transport. Melanotransferrin/CD228 also exhibits potential zinc binding, showcasing versatile metal ion interactions. Melanotransferrin/CD228 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Melanotransferrin/CD228 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Melanotransferrin/CD228 Protein, Mouse (HEK293, Fc) is 708 a.a., with molecular weight of ~100 KDa.

For research use only. We do not sell to patients.

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Description

Melanotransferrin/CD228 protein is involved in cellular iron uptake, undergoing internalization and recycling to the cell membrane. Each subunit binds a single iron atom, suggesting a role in intracellular iron transport. Melanotransferrin/CD228 also exhibits potential zinc binding, showcasing versatile metal ion interactions. Melanotransferrin/CD228 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Melanotransferrin/CD228 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Melanotransferrin/CD228 Protein, Mouse (HEK293, Fc) is 708 a.a., with molecular weight of ~100 KDa.
Background

Melanotransferrin/CD228 protein is implicated in cellular iron uptake, where it appears to undergo internalization and subsequent recycling back to the cell membrane. Each subunit of this protein has the capacity to bind a single atom of iron, suggesting its role in intracellular iron transport. Additionally, Melanotransferrin/CD228 could potentially bind zinc, indicating a versatility in metal ion binding capabilities.
Species

Mouse
Source

HEK293
Tag

C-hFc
Accession

Q9R0R1 (M1-Q708)
Gene ID

30060  [NCBI]
Molecular Construction
N-term
Melanotransferrin (M1-Q708)
Accession # Q9R0R1
hFc
C-term
Synonyms
Melanotransferrin; MTf; CD228; MELTF; MFI2
Molecular Weight

Approximately 100 kDa.
Purity

Greater than 90% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

Melanotransferrin/CD228 Protein, Mouse (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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