METTL2A Protein, Human (sf9, GST)
METTL2A Protein, Human (sf9, GST) is the recombinant human-derived METTL2A, expressed by Sf9 insect cells , with GST labeled tag. ,
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
METTL2A Protein, Human (sf9, GST) is the recombinant human-derived METTL2A, expressed by Sf9 insect cells , with GST labeled tag. ,
Background
METTL2A is an S-adenosyl-L-methionine-dependent methyltransferase that catalyzes N(3)-methylcytidine modification at position 32 of the anticodon loop in tRNA(Thr)(UGU) and tRNA(Arg)(CCU). The N(3)-methylcytidine methylation by METTL2A requires prior N6-threonylcarbamoylation (t6A37) of tRNA by the EKC/KEOPS complex. by similar: This function is shared with METTL2B.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag GST
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Accession
Q96IZ6-1 (M1-S378)
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Gene ID339175
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Protein Length
Full Length of Isoform-1
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Synonyms
METTL2A; Methyltransferase-Like Protein 2A; Methyltransferase 2A, TRNA N3-Cytidine; Methyltransferase Like 2A; METTL2; FLJ12760; TRNA N(3)-Cytidine Methyltransferase METTL2A; TRNA N(3)-Methylcytidine Methyltransferase METTL2A; Methyltransferase 2A, Methyl
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AA Sequence
MAGSYPEGAPAVLADKRQQFGSRFLRDPARVFHHNAWDNVEWSEEQAAAAERKVQENSIQRVCQEKQVDYEINAHKYWNDFYKIHENGFFKDRHWLFTEFPELAPSQNQNHLKDWFLENKSEVPECRNNEDGPGLIMEEQHKCSSKSLEHKTQTLPVEENVTQKISDLEICADEFPGSSATYRILEVGCGVGNTVFPILQTNNDPGLFVYCCDFSSTAIELVQTNSEYDPSRCFAFVHDLCDEEKSYPVPKGSLDIIILIFVLSAIVPDKMQKAINRLSRLLKPGGMMLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQEELDTLFTTAGLEKVQNLVDRRLQVNRGKQLTMYRVWIQCKYCKPLLSSTS
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Molecular Weight
Approximately 69 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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