PCDH10 Protein, Human (L405P, HEK293, His)

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The PCDH10 protein is a putative calcium-dependent cell adhesion protein implicated in mediating cell-cell interactions. Its response to intracellular calcium levels is characteristic of cell adhesion molecules, suggesting a role in cell recognition, adhesion and signaling. PCDH10 Protein, Human (L405P, HEK293, His) is the recombinant human-derived PCDH10 protein, expressed by HEK293 , with C-6*His labeled tag and L405P mutation.

For research use only. We do not sell to patients.
  • Species: Human
  • Source: HEK293
  • Storage:
    Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
  • Biological Activity
  • Technical Parameters
  • Product Properties
  • Documentation
  • Help & FAQs

Biological Activity

Description

The PCDH10 protein is a putative calcium-dependent cell adhesion protein implicated in mediating cell-cell interactions. Its response to intracellular calcium levels is characteristic of cell adhesion molecules, suggesting a role in cell recognition, adhesion and signaling. PCDH10 Protein, Human (L405P, HEK293, His) is the recombinant human-derived PCDH10 protein, expressed by HEK293 , with C-6*His labeled tag and L405P mutation.

Background

PCDH10 Protein presents itself as a potential calcium-dependent cell-adhesion protein, suggesting a role in mediating cell-cell interactions. The protein's calcium dependence implies its responsiveness to intracellular calcium levels, which is a characteristic feature of many cell-adhesion molecules involved in processes such as cell recognition, adhesion, and signaling. PCDH10's putative function as a cell-adhesion protein suggests its involvement in maintaining tissue integrity and regulating cellular behavior within diverse biological contexts. Further exploration of its molecular interactions and cellular functions may offer valuable insights into its specific roles in cell adhesion and its potential implications in various physiological processes.

Technical Parameters

  • Species Human
  • Source HEK293
  • Tag C-6*His
  • Accession
  • Gene ID
  • Molecular Construction
    • N-term
    • PCDH10 (Q19-T715, L405P)
      Accession # Q9P2E7-1
    • 6*His
    • C-term
  • Protein Length

    Extracellular Domain

  • Synonyms

    PCDH10; Protocadherin-10; Protocadherin 10; Protocadherin 10 Isoform B; KIAA1400; Protocadherin 10 Isoform A; OL-PCDH

  • AA Sequence

    QLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRPKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLT

  • Predicted Molecular Mass

    76.4 kDa

  • Molecular Weight

    Approximately 87 kDa, based on SDS-PAGE under reducing conditions.

  • Glycosylation

    Yes

  • Purity

    ≥ 95%, as determined by reducing SDS-PAGE.

Product Properties

Appearance

Lyophilized powder.

Formulation

Lyophilized from a 0.22 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Storage & Stability

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Calculators

Reconstitution Calculator

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) Volume (to add to vial)
=
Mass (in vial) Mass (in vial)
÷
Desired Reconstitution Concentration Desired Reconstitution Concentration
Dilution Calculator

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

Concentration (start) Concentration (start)
×
Volume (start) Volume (start)
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The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
Unit/mg
= 106 ÷
Biological Activity (ED50) Biological Activity (ED50)
106 ÷
ng/mL
MOQ
Minimum order quantity
100 mg

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