PRRG2 Protein, Human (HEK293, Fc)
Based on 1 Customer Validation
PRRG2 protein interacts with NEDD4, suggesting a role in cellular regulation. In addition, it associates with the transcriptional coactivator YAP1, suggesting a possible involvement in transcriptional regulation. PRRG2 Protein, Human (HEK293, Fc) is the recombinant human-derived PRRG2 protein, expressed by HEK293 , with C-mFc labeled tag.
- Species: Human
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
PRRG2 protein interacts with NEDD4, suggesting a role in cellular regulation. In addition, it associates with the transcriptional coactivator YAP1, suggesting a possible involvement in transcriptional regulation. PRRG2 Protein, Human (HEK293, Fc) is the recombinant human-derived PRRG2 protein, expressed by HEK293 , with C-mFc labeled tag.
Background
The PRRG2 protein exhibits specific molecular interactions, including its association with NEDD4, indicating a potential role in cellular regulatory processes. Moreover, PRRG2 interacts with the transcriptional coactivator YAP1 via its cytoplasmic domain, suggesting a possible involvement in modulating transcriptional activities. These interactions highlight the intricate nature of PRRG2 and imply its participation in diverse cellular functions and signaling pathways, warranting further investigation into the specific mechanisms and functional consequences of these protein associations.
Verified Bioactivity
The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.
MCE Validation Data
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Purity - SDS-PAGE
Purity - SDS-PAGE
Technical Parameters
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Species Human
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Source HEK293
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Tag C-mFc
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Accession
O14669 (E29-S109)
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Gene ID5639 [NCBI]
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Molecular Construction
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N-term
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PRRG2 (E29-S109)
Accession # O14669 -
mFc
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C-term
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Protein Length
Partial Extracellular Domain
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Synonyms
PRRG2; Proline-Rich Gla Protein 2; Proline Rich And Gla Domain 2; Proline-Rich Gla (G-Carboxglutamic Acid) Polypeptide 2; PRGP2; Proline Rich Gla (G-Carboxyglutamic Acid) 2; Proline-Rich Gla (G-Carboxyglutamic Acid) Polypeptide 2; PRRG2 Protein; Transmemb
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AA Sequence
EVFLGPPEAQSFLSSHTRIPRANHWDLELLTPGNLERECLEERCSWEEAREYFEDNTLTERFWESYIYNGKGGRGRVDVAS
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Molecular Weight
Approximately 37 kDa.
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
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Data Sheet (235 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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