PSMD7 Protein, Human (Sf9)

The PSMD7 protein is a component of the 26S proteasome and promotes the ATP-dependent degradation of ubiquitinated proteins. It maintains protein homeostasis by eliminating misfolded or unnecessary proteins, thereby protecting cellular function. PSMD7 Protein, Human (Sf9) is the recombinant human-derived PSMD7 protein, expressed by Sf9 insect cells , with tag free. The total length of PSMD7 Protein, Human (Sf9) is 323 a.a., .

PSMD7, a vital component of the 26S proteasome, forms part of the multiprotein complex responsible for the ATP-dependent degradation of ubiquitinated proteins. This complex plays a crucial role in maintaining protein homeostasis by eliminating misfolded or damaged proteins, which could otherwise impede cellular functions, as well as proteins that are no longer necessary for cellular processes such as cell cycle progression, apoptosis, or DNA damage repair. PSMD7 is a member of the 19S proteasome regulatory particle complex, which constitutes the lid of the 26S proteasome and is composed of nine subunits, including PSMD7, along with a base containing six ATPases and a few additional components. Within this complex, PSMD7 interacts with subunit PSMD4 through their respective MPN domains. Moreover, PSMD7 engages in interactions with TRIM5, highlighting its role in diverse cellular processes and protein-protein interactions.

Human

Sf9 insect cells

Tag Free

P51665 (P2-K324)

5713

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.