PSMD7 Protein, Human (sf9)
The PSMD7 protein is a component of the 26S proteasome and promotes the ATP-dependent degradation of ubiquitinated proteins. It maintains protein homeostasis by eliminating misfolded or unnecessary proteins, thereby protecting cellular function. PSMD7 Protein, Human (sf9) is the recombinant human-derived PSMD7 protein, expressed by sf9 insect cells , with tag free.
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
The PSMD7 protein is a component of the 26S proteasome and promotes the ATP-dependent degradation of ubiquitinated proteins. It maintains protein homeostasis by eliminating misfolded or unnecessary proteins, thereby protecting cellular function. PSMD7 Protein, Human (sf9) is the recombinant human-derived PSMD7 protein, expressed by sf9 insect cells , with tag free.
PSMD7, a vital component of the 26S proteasome, forms part of the multiprotein complex responsible for the ATP-dependent degradation of ubiquitinated proteins. This complex plays a crucial role in maintaining protein homeostasis by eliminating misfolded or damaged proteins, which could otherwise impede cellular functions, as well as proteins that are no longer necessary for cellular processes such as cell cycle progression, apoptosis, or DNA damage repair. PSMD7 is a member of the 19S proteasome regulatory particle complex, which constitutes the lid of the 26S proteasome and is composed of nine subunits, including PSMD7, along with a base containing six ATPases and a few additional components. Within this complex, PSMD7 interacts with subunit PSMD4 through their respective MPN domains. Moreover, PSMD7 engages in interactions with TRIM5, highlighting its role in diverse cellular processes and protein-protein interactions.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag Tag Free
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Accession
P51665 (P2-K324)
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Gene ID5713
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Molecular Construction
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N-term
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PSMD7 (P2-K324)
Accession # P51665 -
C-term
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Protein Length
Partial
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Synonyms
PSMD7; Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 7 (Mov34 Homolog); Proteasome 26S Subunit, Non-ATPase 7; 26S Proteasome Regulatory Subunit RPN8; 26S Proteasome Non-ATPase Regulatory Subunit 7; Mov34 Homolog; 26S Proteasome Regulatory Subun
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AA Sequence
PELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKKVLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPNSVLVIIDVKPKDLGLPTEAYISVEEVHDDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRSYLEKVATGKLPINHQIIYQLQDVFNLLPDVSLQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIANRDAEKKEGQEKEESKKDRKEDKEKDKDKEKSDVKKEEKKEKK
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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