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  4. REG4 Protein, Mouse (His)

REG4 protein, a calcium-independent lectin, binds specifically to mannose and maintains carbohydrate recognition in acidic environments. It is implicated in the inflammatory and metaplastic responses of the gastrointestinal epithelium. REG4 Protein, Mouse (His) is the recombinant mouse-derived REG4 protein, expressed by E. coli , with C-10*His tag.

For research use only. We do not sell to patients.

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Description

REG4 protein, a calcium-independent lectin, binds specifically to mannose and maintains carbohydrate recognition in acidic environments. It is implicated in the inflammatory and metaplastic responses of the gastrointestinal epithelium. REG4 Protein, Mouse (His) is the recombinant mouse-derived REG4 protein, expressed by E. coli , with C-10*His tag.
Background

REG4 protein is a calcium-independent lectin that exhibits a specific binding affinity for mannose and retains its ability to recognize carbohydrates even in acidic environments. It is believed to play a role in the inflammatory and metaplastic responses of the gastrointestinal epithelium.
Species

Mouse
Source

E. coli
Tag

C-10*His
Accession

NP_080604.2/Q9D8G5 (D23-T157)
Gene ID
Molecular Construction
N-term
REG4 (D23-T157)
Accession # NP_080604.2/Q9D8G5
10*His
C-term
Protein Length

Full Length of Mature Protein
Synonyms
Regenerating islet-derived protein 4; Reg4; REG-4; Regenerating Islet-derived 4
AA Sequence

DILRPSCAPGWFYYRSHCYGYFRKLRNWSHAELECQSYGNGSHLASVLNQKEASVISKYITGYQRNLPVWIGLHDPQKKQLWQWTDGSTNLYRRWNPRTKSEARHCAEMNPKDKFLTWNKNGCANRQHFLCKYKT

Predicted Molecular Mass
17.5 kDa
Molecular Weight

Approximately 23-30 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation .
Glycosylation
Yes
Purity

≥ 95%, as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

REG4 Protein, Mouse (His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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