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SEZ6L2//BSRP-A Protein, Human (HEK293, His)

Cat. No.: HY-P77200
COA Handling Instructions

SEZ6L2/BSRP-A, potentially contributing to specialized functions in the endoplasmic reticulum (ER) of neurons, hints at a role critical for neuronal homeostasis. Its significance in the intricate molecular processes essential for neuronal function underscores the need for further exploration to unveil specific mechanisms and pathways through which SEZ6L2/BSRP-A participates in specialized ER functions. SEZ6L2//BSRP-A Protein, Human (HEK293, His) is the recombinant human-derived SEZ6L2//BSRP-A protein, expressed by HEK293 , with C-His labeled tag. The total length of SEZ6L2//BSRP-A Protein, Human (HEK293, His) is 709 a.a., with molecular weight of 104-117 kDa.

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Description

SEZ6L2/BSRP-A, potentially contributing to specialized functions in the endoplasmic reticulum (ER) of neurons, hints at a role critical for neuronal homeostasis. Its significance in the intricate molecular processes essential for neuronal function underscores the need for further exploration to unveil specific mechanisms and pathways through which SEZ6L2/BSRP-A participates in specialized ER functions. SEZ6L2//BSRP-A Protein, Human (HEK293, His) is the recombinant human-derived SEZ6L2//BSRP-A protein, expressed by HEK293 , with C-His labeled tag. The total length of SEZ6L2//BSRP-A Protein, Human (HEK293, His) is 709 a.a., with molecular weight of 104-117 kDa.

Background

The SEZ6L2/BSRP-A protein emerges as a potential contributor to specialized functions within the endoplasmic reticulum (ER) of neurons. The precise nature of its involvement in ER activities remains to be fully elucidated, but the association suggests a role in orchestrating specific functions critical for neuronal homeostasis. SEZ6L2/BSRP-A's potential contributions to the specialized functions within the ER underscore its significance in the intricate molecular processes essential for neuronal function and cellular dynamics. Further exploration is warranted to uncover the specific mechanisms and pathways through which SEZ6L2/BSRP-A participates in these specialized ER functions, shedding light on its role in neuronal physiology.

Species

Human

Source

HEK293

Tag

C-His

Accession

Q6UXD5 (L28-G736)

Gene ID
Molecular Construction
N-term
SEZ6L2 (L28-G736)
Accession # Q6UXD5
His
C-term
Synonyms
Seizure 6-like protein 2; PSK; BSRPA
AA Sequence

LPLKEEEILPEPGSETPTVASEALAELLHGALLRRGPEMGYLPGSDRDPTLATPPAGQTLAVPSLPRATEPGTGPLTTAVTPNGVRGAGPTAPELLTPPPGTTAPPPPSPASPGPPLGPEGGEEETTTTIITTTTVTTTVTSPVLCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPG

Molecular Weight

Approximately 110-150 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE

Appearance

Lyophilized powder

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation

SEZ6L2//BSRP-A Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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SEZ6L2//BSRP-A Protein, Human (HEK293, His)
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