SPG21 Protein, Human (sf9, GST)

The SPG21 protein may act as a negative regulator in CD4-dependent T cell activation, suggesting its role in regulating immune responses. Its interaction with CD4 suggests a molecular link affecting CD4-mediated T cell activation pathways. SPG21 Protein, Human (sf9, GST) is the recombinant human-derived SPG21 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of SPG21 Protein, Human (sf9, GST) is 308 a.a., with molecular weight of ~61 kDa.

The SPG21 protein is suggested to potentially function as a negative regulatory factor in CD4-dependent T-cell activation, indicating its involvement in modulating immune responses. It interacts with CD4, suggesting a molecular association that may impact CD4-mediated T-cell activation pathways. Additionally, SPG21 interacts with ALDH16A1, indicating its potential participation in cellular processes associated with the aldehyde dehydrogenase family. The specific mechanisms underlying SPG21's regulatory role in T-cell activation and its interaction with ALDH16A1 remain areas of interest, highlighting its potential significance in immune regulation and cellular metabolism.

Human

Sf9 insect cells

N-GST

Q9NZD8 (M1-Q308)

51324  [NCBI]

Approximately 61 kDa

Greater than 90% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.