SPG21 Protein, Mouse (sf9, His-GST)

The SPG21 protein acts as a negative regulator in CD4-dependent T cell activation, suggesting a potential role in the regulation of immune responses. By interacting directly with CD4, it affects key components of the T cell activation pathway. SPG21 Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived SPG21 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of SPG21 Protein, Mouse (sf9, His-GST) is 308 a.a., with molecular weight of ~52 kDa.

The SPG21 protein appears to function as a negative regulatory factor in CD4-dependent T-cell activation, suggesting a potential role in modulating immune responses. This regulatory function involves direct interactions with CD4, emphasizing its influence on key components of the T-cell activation pathway. Additionally, SPG21 protein interacts with ALDH16A1, indicating its involvement in diverse molecular interactions that may extend beyond T-cell regulation. Further exploration into the specific mechanisms and downstream effects of SPG21 in the context of CD4-dependent T-cell activation could provide valuable insights into its role in immune modulation and cellular processes beyond the immune system.

Mouse

Sf9 insect cells

N-His;N-GST

Q9CQC8 (M1-P308)

27965  [NCBI]

Approximately 52 kDa

Greater than 90% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.