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  5. Syndecan-1/CD138 Protein, Rat (P.pastoris, His)

Syndecan-1/CD138 Protein, Rat (P.pastoris, His)

Cat. No.: HY-P71782
Handling Instructions

Syndecan-1 (CD138) is a cell surface proteoglycan containing heparan sulfate and chondroitin sulfate that connects the cytoskeleton to the interstitial matrix. Syndecan-1/CD138 Protein, Rat (P.pastoris, His) is the recombinant rat-derived Syndecan-1/CD138 protein, expressed by P. pastoris , with N-His labeled tag. The total length of Syndecan-1/CD138 Protein, Rat (P.pastoris, His) is 235 a.a., with molecular weight of ~26.5 kDa.

For research use only. We do not sell to patients.

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Description

Syndecan-1 (CD138) is a cell surface proteoglycan containing heparan sulfate and chondroitin sulfate that connects the cytoskeleton to the interstitial matrix. Syndecan-1/CD138 Protein, Rat (P.pastoris, His) is the recombinant rat-derived Syndecan-1/CD138 protein, expressed by P. pastoris , with N-His labeled tag. The total length of Syndecan-1/CD138 Protein, Rat (P.pastoris, His) is 235 a.a., with molecular weight of ~26.5 kDa.

Background

Syndecan-1/CD138 Protein is a cell surface proteoglycan characterized by the presence of both heparan sulfate and chondroitin sulfate, establishing a link between the cytoskeleton and the interstitial matrix. It plays a role in regulating exosome biogenesis in collaboration with SDCBP and PDCD6IP. Moreover, Syndecan-1/CD138 has the capacity to induce its own expression in dental mesenchymal cells and neighboring dental epithelial cells through an MSX1-mediated pathway. It interacts with CDCP1 and associates with TIAM1 via its C-terminus and the PDZ domain of TIAM1. Additionally, Syndecan-1/CD138 engages in an interaction with Midkine (MDK).

Species

Rat

Source

P. pastoris

Tag

N-His

Accession

P26260 (23Q-257G)

Gene ID

25216  [NCBI]

Molecular Construction
N-term
His
CD138 (23Q-257G)
Accession # P26260
C-term
Synonyms
Sdc1; Synd1; Syndecan-1; SYND1; CD antigen CD138
AA Sequence

QIVTANVPPEDQDGSGDDSDNFSGSGTGALPDMTLSRQTPSTWKDVWLLTATPTAPEPTSRDTEATLTSILPAGEKPEEGEPVAHVEAEPDFTARDKEKEATTRPRETTQLPVTQQASTAARATTAQASVTSHPHGDVQPGLHETLAPTAPGQPDHQPPSVEDGGTSVIKEVVEDETTNQLPAGEGSGEQDFTFETSGENTAVAGVEPDLRNQSPVDEGATGASQGLLDRKEVLG

Molecular Weight

Approximately 26.5 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

Syndecan-1/CD138 Protein, Rat (P.pastoris, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Syndecan-1/CD138 Protein, Rat (P.pastoris, His)
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HY-P71782
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