Syndecan-1/CD138 Protein, Rat (P.pastoris, His)
Syndecan-1 (CD138) is a cell surface proteoglycan containing heparan sulfate and chondroitin sulfate that connects the cytoskeleton to the interstitial matrix.Syndecan-1/CD138 Protein, Rat (P.pastoris, His) is the recombinant rat-derived Syndecan-1/CD138 protein, expressed by P.pastoris , with N-His labeled tag.
- Species: Rat
- Source: P. pastoris
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
Syndecan-1 (CD138) is a cell surface proteoglycan containing heparan sulfate and chondroitin sulfate that connects the cytoskeleton to the interstitial matrix.Syndecan-1/CD138 Protein, Rat (P.pastoris, His) is the recombinant rat-derived Syndecan-1/CD138 protein, expressed by P.pastoris , with N-His labeled tag.
Background
Syndecan-1/CD138 Protein is a cell surface proteoglycan characterized by the presence of both heparan sulfate and chondroitin sulfate, establishing a link between the cytoskeleton and the interstitial matrix. It plays a role in regulating exosome biogenesis in collaboration with SDCBP and PDCD6IP. Moreover, Syndecan-1/CD138 has the capacity to induce its own expression in dental mesenchymal cells and neighboring dental epithelial cells through an MSX1-mediated pathway. It interacts with CDCP1 and associates with TIAM1 via its C-terminus and the PDZ domain of TIAM1. Additionally, Syndecan-1/CD138 engages in an interaction with Midkine (MDK).
Technical Parameters
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Species Rat
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Source P. pastoris
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Tag N-His
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Accession
P26260 (Q23-G257)
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Molecular Construction
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N-term
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His
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CD138 (Q23-G257)
Accession # P26260 -
C-term
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Protein Length
Extracellular Domain
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Synonyms
SDC1; CD138; Prev. SDC; CD138 Antigen; SYND1; Syndecan-1; Syndecan; Heparan Sulfate Proteoglycan Fibroblast Growth Factor Receptor; Syndecan 1; Syndecan Proteoglycan 1
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AA Sequence
QIVTANVPPEDQDGSGDDSDNFSGSGTGALPDMTLSRQTPSTWKDVWLLTATPTAPEPTSRDTEATLTSILPAGEKPEEGEPVAHVEAEPDFTARDKEKEATTRPRETTQLPVTQQASTAARATTAQASVTSHPHGDVQPGLHETLAPTAPGQPDHQPPSVEDGGTSVIKEVVEDETTNQLPAGEGSGEQDFTFETSGENTAVAGVEPDLRNQSPVDEGATGASQGLLDRKEVLG
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Predicted Molecular Mass
26.5 kDa
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Glycosylation
Yes
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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