TDGF1P3 Protein, Human (P. pastoris, His)
The TDGF1P3 protein is a protein that may be involved in the determination of ectodermal cells, which in turn contribute to mesoderm development. Its effects are exerted through activation of node-dependent signaling pathways, suggesting its role in complex processes regulating cell fate and tissue differentiation. TDGF1P3 Protein, Human (P. pastoris, His) is the recombinant human-derived TDGF1P3 protein, expressed by P. pastoris , with C-6*His labeled tag.
- Species: Human
- Source: P. pastoris
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
The TDGF1P3 protein is a protein that may be involved in the determination of ectodermal cells, which in turn contribute to mesoderm development. Its effects are exerted through activation of node-dependent signaling pathways, suggesting its role in complex processes regulating cell fate and tissue differentiation. TDGF1P3 Protein, Human (P. pastoris, His) is the recombinant human-derived TDGF1P3 protein, expressed by P. pastoris , with C-6*His labeled tag.
Background
TDGF1P3 Protein is a protein that shows potential involvement in the determination of epiblastic cells, which in turn contribute to mesodermal development. Its influence is exerted through the activation of the Nodal-dependent signaling pathway, indicating its role in the complex processes that regulate cellular fate and tissue differentiation. By activating this signaling pathway, TDGF1P3 Protein likely plays a critical role in orchestrating the development and differentiation of cells during embryogenesis and embryonic tissue formation. Further investigation is required to fully understand the precise mechanisms by which TDGF1P3 Protein functions in these processes and its specific interactions within the Nodal-dependent signaling pathway.
Technical Parameters
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Species Human
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Source P. pastoris
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Tag C-6*His
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Accession
P51864 (L31-Y188)
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Gene ID6998 [NCBI]
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Molecular Construction
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N-term
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TDGF1P3 (L31-Y188)
Accession # P51864 -
6*His
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C-term
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Protein Length
Partial
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Synonyms
CRIPTO3; Teratocarcinoma-Derived Growth Factor 3; Prev. TDGF1P3; Protein CRIPTO3; Prev. TDGF3; Teratocarcinoma-Derived Growth Factor 2 (Retroposin, Possibly Expressed); CRIPTO-3; Teratocarcinoma-Derived Growth Factor 3, Pseudogene; TDGF2; Putative Teratoc
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AA Sequence
LGHQEFARPSRGDLAFRDDSIWPQEEPAIRPRSSQRVLPMGIQHSKELNRTCCLNGGTCMLESFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLRCFPQAFLPGCDGLVMDEHLVASRTPELPPSARTTTFMLAGICLSIQSYY
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Predicted Molecular Mass
18.6 kDa
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Glycosylation
Yes
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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