Testican 3/SPOCK3 Protein, Mouse (sf9, His)

The Testican 3/SPOCK3 protein may be involved in different steps of neurogenesis, suggesting a multifaceted role in neuronal cell development. It inhibits pro-matrix metalloproteinase 2 (MMP-2) processing through MT1-MMP and MT3-MMP and regulates MMP-2 activity. Testican 3/SPOCK3 Protein, Mouse (sf9, His) is the recombinant mouse-derived Testican 3/SPOCK3 protein, expressed by Sf9 insect cells , with C-His labeled tag.

Testican 3/SPOCK3 protein is implicated in potentially participating in diverse steps of neurogenesis, suggesting its multifaceted role in the intricate processes of neural cell development. Additionally, it inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP, indicating a regulatory function in the modulation of MMP-2 activity. Furthermore, Testican 3/SPOCK3 may interfere with tumor invasion, as suggested by similarity with other proteins. The comprehensive functions attributed to Testican 3/SPOCK3 underscore its significance in both neurodevelopmental processes and potential involvement in the regulation of extracellular matrix dynamics related to tumor invasion.

Mouse

Sf9 insect cells

C-His

Q8BKV0-1 (A23-I436)

72902  [NCBI]

Full Length of Isoform-1 Mature Protein

AAAVAVAGGRSDGGNFLDEKQWLTTISQYDKEVGQWNKFRDEVEDDYFRTWNPGKPFDQALDPAKDPCLKTKCSRHKVCITQDAQTALCISHRRLTHSMKEVGGSHKQWRGLPSSTCKPCPIAYASPVCGSDGHSYSSQCKLEYQACVLGKQISIKCEGRCPCPSDKSMNIGRNVKRACSDLEFREVANRLRDWFKALHESGSQNKKTKALLRPERSRFDTSILPICKDSLGWMFNRLDTNYDLLLDQSELGSIYLDKNEQCTKAFFNSCDTYKDSLISNNEWCYCFQRQQDPPCHTELSNIQKRQGIKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVVGSRINGVADCAIDFEISGDFASGDFREWTDDEGEEDDIMNDKDDIEDDDEDEGDDDDDGDVHDGYI

≥ 90%, as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.