Testican 3/SPOCK3 Protein, Mouse (sf9, His)
The Testican 3/SPOCK3 protein may be involved in different steps of neurogenesis, suggesting a multifaceted role in neuronal cell development. It inhibits pro-matrix metalloproteinase 2 (MMP-2) processing through MT1-MMP and MT3-MMP and regulates MMP-2 activity. Testican 3/SPOCK3 Protein, Mouse (sf9, His) is the recombinant mouse-derived Testican 3/SPOCK3 protein, expressed by Sf9 insect cells , with C-His labeled tag.
- Species: Mouse
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
The Testican 3/SPOCK3 protein may be involved in different steps of neurogenesis, suggesting a multifaceted role in neuronal cell development. It inhibits pro-matrix metalloproteinase 2 (MMP-2) processing through MT1-MMP and MT3-MMP and regulates MMP-2 activity. Testican 3/SPOCK3 Protein, Mouse (sf9, His) is the recombinant mouse-derived Testican 3/SPOCK3 protein, expressed by Sf9 insect cells , with C-His labeled tag.
Background
Testican 3/SPOCK3 protein is implicated in potentially participating in diverse steps of neurogenesis, suggesting its multifaceted role in the intricate processes of neural cell development. Additionally, it inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP, indicating a regulatory function in the modulation of MMP-2 activity. Furthermore, Testican 3/SPOCK3 may interfere with tumor invasion, as suggested by similarity with other proteins. The comprehensive functions attributed to Testican 3/SPOCK3 underscore its significance in both neurodevelopmental processes and potential involvement in the regulation of extracellular matrix dynamics related to tumor invasion.
Technical Parameters
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Species Mouse
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Source Sf9 insect cells
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Tag C-His
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Accession
Q8BKV0-1 (A23-I436)
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Molecular Construction
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N-term
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SPOCK3 (A23-I436)
Accession # Q8BKV0-1 -
His
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C-term
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Protein Length
Full Length of Isoform-1
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Synonyms
SPOCK3; CDNA FLJ59873, Highly Similar To Testican-3; SPARC (Osteonectin), Cwcv And Kazal Like Domains Proteoglycan 3; Uncharacterized Protein Tmp_locus_3; Testican-3; Alternative Protein SPOCK3; Sparc/Osteonectin, Cwcv And Kazal-Like Domains Proteoglycan
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AA Sequence
AAAVAVAGGRSDGGNFLDEKQWLTTISQYDKEVGQWNKFRDEVEDDYFRTWNPGKPFDQALDPAKDPCLKTKCSRHKVCITQDAQTALCISHRRLTHSMKEVGGSHKQWRGLPSSTCKPCPIAYASPVCGSDGHSYSSQCKLEYQACVLGKQISIKCEGRCPCPSDKSMNIGRNVKRACSDLEFREVANRLRDWFKALHESGSQNKKTKALLRPERSRFDTSILPICKDSLGWMFNRLDTNYDLLLDQSELGSIYLDKNEQCTKAFFNSCDTYKDSLISNNEWCYCFQRQQDPPCHTELSNIQKRQGIKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVVGSRINGVADCAIDFEISGDFASGDFREWTDDEGEEDDIMNDKDDIEDDDEDEGDDDDDGDVHDGYI
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Predicted Molecular Mass
48.3 kDa
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Glycosylation
Yes
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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