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Transferrin Protein, Mouse (HEK293, Fc)

Cat. No.: HY-P73581
Handling Instructions

Transferrin is an important iron-binding transport protein that combines two Fe(3+) ions with an anion, usually bicarbonate. Its main function is to transport iron from the site of absorption to the site of storage and utilization. Transferrin Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Transferrin protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Transferrin Protein, Mouse (HEK293, Fc) is 697 a.a., with molecular weight of ~102 kDa.

For research use only. We do not sell to patients.

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Description

Transferrin is an important iron-binding transport protein that combines two Fe(3+) ions with an anion, usually bicarbonate. Its main function is to transport iron from the site of absorption to the site of storage and utilization. Transferrin Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Transferrin protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Transferrin Protein, Mouse (HEK293, Fc) is 697 a.a., with molecular weight of ~102 kDa.

Background

Transferrin, a pivotal iron-binding transport protein, exhibits the capacity to bind two Fe(3+) ions in conjunction with an anion, typically bicarbonate. Its primary responsibility lies in facilitating the transport of iron from absorption sites and heme degradation to locations designated for storage and utilization within the body. Beyond its fundamental role in iron homeostasis, serum transferrin may additionally play a role in promoting cell proliferation. Structured as a monomer, transferrin's multifaceted functions underscore its significance in orchestrating the intricate balance of iron distribution and cellular processes essential for overall physiological well-being.

Species

Mouse

Source

HEK293

Tag

C-hFc

Accession

Q921I1 (M1-H697)

Gene ID

22041  [NCBI]

Molecular Construction
N-term
Transferrin (M1-H697)
Accession # Q921I1
hFc
C-term
Synonyms
Serotransferrin; Transferrin; Beta-1 metal-binding globulin; Siderophilin; TF; TRF
Molecular Weight

Approximately 102 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

Transferrin Protein, Mouse (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
Transferrin Protein, Mouse (HEK293, Fc)
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HY-P73581
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