TSSK1 Protein, Human (Active, sf9, His-GST)
The TSSK1 protein is a testis-specific serine/threonine protein kinase that plays a crucial role during late spermatogenesis, especially during cytoplasmic remodeling. It phosphorylates "Ser-288" of TSKS, which contributes to the transition of the ring structure around the base of the flagellum. TSSK1, Human (Active, sf9, His-GST) is the recombinant human-derived TSSK1 protein, expressed by Sf9 insect cells, with N-6*His;N-GST labeled tag.
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
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Biological Activity
Description
The TSSK1 protein is a testis-specific serine/threonine protein kinase that plays a crucial role during late spermatogenesis, especially during cytoplasmic remodeling. It phosphorylates "Ser-288" of TSKS, which contributes to the transition of the ring structure around the base of the flagellum. TSSK1, Human (Active, sf9, His-GST) is the recombinant human-derived TSSK1 protein, expressed by Sf9 insect cells, with N-6*His;N-GST labeled tag.
Background
The TSSK1 protein, a testis-specific serine/threonine-protein kinase, emerges as a crucial factor in spermatid development, particularly in the late stages of spermatogenesis during cytoplasm reconstruction. Its role involves phosphorylating 'Ser-288' of TSKS and contributing to the transformation of a ring-shaped structure surrounding the base of the flagellum, originating from the chromatoid body. TSSK1's involvement in these intricate processes underscores its significance in the precise orchestration of events essential for spermatid maturation. This testis-specific kinase plays a vital role in the intricate molecular events that underlie spermatogenesis, contributing to the structural changes and developmental transitions necessary for the formation of mature sperm cells.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag N-6*His;N-GST
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Accession
Q9BXA7 (M1-Q367)
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Gene ID83942
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Molecular Construction
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N-term
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6*His-GST
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TSSK1B (M1-Q367)
Accession # Q9BXA7 -
C-term
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Protein Length
Full Length
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Synonyms
TSSK1B; Testis Specific Serine Kinase 1B; STK22D; TSSK1; SPOGA4; FKSG81; Serine/Threonine Kinase 22D (Spermiogenesis Associated); Testis-Specific Serine/Threonine-Protein Kinase 1; Serine/Threonine-Protein Kinase 22A; Testis-Specific Serine Kinase 1; Test
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Predicted Molecular Mass
70.7 kDa
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Purity
≥ 85%, as determined by reducing SDS-PAGE.
Product Properties
Solution
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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