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Cat. No.: HY-12216R

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Resmetirom (Standard)

Name: Resmetirom (Standard)
Brand: MedChemExpress
SKU: HY-12216R
Availability: PreOrder

(Synonyms: MGL-3196 (Standard); VIA-3196 (Standard))

Resmetirom (Standard) is the analytical standard of Resmetirom (HY-12216). This product is intended for research and analytical applications. Resmetirom (MGL-3196) is a highly selective and orally active thyroid hormone receptor β (THR-β) agonist with an EC₅₀ value of 0.21 μM. Resmetirom can be used for the study of noncirrhotic nonalcoholic steatohepatitis.

For research use only. We do not sell to patients.

CAS No.: 920509-32-6
Formula: C₁₇H₁₂Cl₂N₆O₄
Molecular Weight:435.22

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Resmetirom (Standard) Chemical Structure

CAS No.: 920509-32-6

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 920509-32-6
Molecular Weight 435.22
Formula C₁₇H₁₂Cl₂N₆O₄
SMILES

N#CC1=NN(C2=CC(Cl)=C(OC(C=C3C(C)C)=NNC3=O)C(Cl)=C2)C(NC1=O)=O
Synonyms

MGL-3196 (Standard); VIA-3196 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Kelly MJ, et al. Discovery of 2-[3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β agonist in clinical trials for the treatment of dyslipidemia. J Med Chem. 2014 May 22;57(10):3912-23. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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