RIPK1 ligand-Linker Conjugate-2
RIPK1 ligand-Linker Conjugate-2 is a conjugate of a RIPK1 ligand and a linker, in which the RIPK1 ligand is RIPK1-IN-37 (HY-179235) and the linker is Boc-2,6-Diazaspiro[3.3]heptane-Py-Ph-acid (HY-189354). RIPK1 ligand-Linker Conjugate-2 can be used to synthesize RIPK1 PROTAC degraders, such as LD5095 (HY-189352).
For research use only. We do not sell to patients.
- Formula: C47H42F3N9O3
- Molecular Weight:837.89
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
RIPK1 |
Chemical Information
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Molecular Weight 837.89
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Formula C47H42F3N9O3
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SMILES
NC1=C2C(C3=CC4=C(N(CC4)C(CC5=CC=CC(OC(F)(F)F)=C5)=O)C=C3)=CN(C2=NC=N1)C6CCN(CC6)C(C7=CC=C(C=C7)C#CC8=CN=C(C=C8)N9CC%10(C9)CNC%10)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)