SARS-CoV-2 Mpro-IN-24
SARS-CoV-2 Mpro-IN-24 (Compound X77) is a inhibitor of SARS-CoV-2 Mpro (IC50=2.8 μM) and also a non-covalent inhibitor of SARS-CoV Mpro (IC50=3.4 μM).
For research use only. We do not sell to patients.
- Formula: C28H34N4O2
- Molecular Weight:458.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
SARS-CoV-2 Mpro 2.8 μM (IC50) |
SARS-CoV Mpro 3.4 μM (IC50) |
Chemical Information
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Molecular Weight 458.60
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Formula C28H34N4O2
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SMILES
CC(C)(C)C1=CC=C(N(C(C2=CNC=N2)=O)[C@H](C3=CC=CC=C3)C(NC4CCCCC4)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)