SARS-CoV-2 nsp14-IN-9
SARS-CoV-2 nsp14-IN-9 (Compound 4P) is a selective nsp14 inhibitor with an IC50 of 0.20 μM. SARS-CoV-2 nsp14-IN-9 inhibits both mouse hepatitis virus and SARS-CoV-2 replication.
For research use only. We do not sell to patients.
- Formula: C21H20BrN5O3S
- Molecular Weight:502.38
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
IC50: 0.20 μM (nsp14)[1]
Chemical Information
-
Molecular Weight 502.38
-
Formula C21H20BrN5O3S
-
SMILES
NC1=C2N=CN([C@H]3[C@H](O)[C@H](O)[C@@H](CSCC4=CC=C5C=CC=CC5=C4Br)O3)C2=NC=N1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)