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  4. Pain
  5. SCH 30497

SCH 30497 is a potent and orally active analgesic agent. SCH 30497 exhibits analgesic activity in the rat yeast-induced paw pain model, the mouse acetic acid-induced writhing test, and the squirrel monkey electric shock titration test. SCH 30497 can be used in pain research.

For research use only. We do not sell to patients.

SCH 30497

SCH 30497 Chemical Structure

CAS No. : 83674-78-6

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Description

SCH 30497 is a potent and orally active analgesic agent. SCH 30497 exhibits analgesic activity in the rat yeast-induced paw pain model, the mouse acetic acid-induced writhing test, and the squirrel monkey electric shock titration test. SCH 30497 can be used in pain research[1].

In Vivo

SCH 30497 demonstrats dose-dependent analgesic effects in a rat model of yeast-induced paw pain; at peak efficacy, the ED50 values ​​(in mg/kg) for oral, subcutaneous, intramuscular, and intravenous administration were 4.7, 5.7, 6.4, and 1.4, respectively[1].
SCH 30497 also exhibits analgesic activity in the mouse acetic acid-induced writhing test (ED50 = 1.9 mg/kg, oral administration) and the squirrel monkey shock titration test (ED50 = 14.5 mg/kg, oral administration)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

348.44

Formula

C21H24N4O
CAS No.
SMILES

O=C1N(N=C2C=CC=CN21)CCCN3CC=C(CC3)C4=CC=CC=C4C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SCH 30497 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SCH 3049783674-78-6SCH30497SCH-30497Othersanalgesicorally activeInhibitorinhibitorinhibit

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