Scutebarbatine W
Scutebarbatine W is a 13-spiro subtype neo-clerodane diterpenoid. Scutebarbatine W inhibits NO production with an IC50 value of 34.7 μM.
For research use only. We do not sell to patients.
- CAS No.: 1312716-25-8
- Formula: C33H37NO8
- Molecular Weight:575.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
IC50: 34.7 μM (NO production)
Chemical Information
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CAS No. 1312716-25-8
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Molecular Weight 575.65
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Formula C33H37NO8
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SMILES
C[C@@]12[C@]3([H])[C@@]([C@H]([C@@H]([C@@]1(O[C@@]4(CC(OC4)=O)CC2)C)O)OC(C5=CN=CC=C5)=O)(C(C)=CC[C@H]3OC(C6=CC=CC=C6)=O)C
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Synonyms
Scutehenanine B
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
[1]. Wang F, et al. Scutebarbatines W-Z, new neo-clerodane diterpenoids from Scutellaria barbata and structure revision of a series of 13-spiro neo-clerodanes. Chem Pharm Bull (Tokyo). 2010 Sep;58(9):1267-70. [Content Brief]
[2]. Lee SR, et al. Constituents from Scutellaria barbata Inhibiting Nitric Oxide Production in LPS-Stimulated Microglial Cells. Chem Biodivers. 2017 Nov;14(11). [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Scutebarbatine W Related Classifications
HY-N1262 Related Classifications
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