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Cat. No.: HY-149323

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SDH-IN-4

SDH-IN-4 (compound B6) is a selective inhibitor against succinate dehydrogenase (SDH) with an IC₅₀ value of 0.28 μg/mL. SDH-IN-4 has highly efficient and broad-spectrum antifungal activity, against R. solani with an EC₅₀ value of 0.23 μg/mL.

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CAS No.: 2982993-88-2
화학식: C₁₁H₉Cl₂F₃N₄O₂S
분자량:389.18

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

SDH-IN-4 Chemical Structure

CAS No.: 2982993-88-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
- In Vivo
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Bioz

Biological Activity

제품 설명

In Vitro

SDH-IN-4 (10 μg/mL, 3-5 days) inhibits mycelium growth of fungal R. solani, F. graminearum, B. cinerea and A. solani^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

SDH-IN-4 (100 μg/mL, 5 days) inhibits R. solani in detached rice leaves was 87.48%^[1].
SDH-IN-4 (20 μg/mL, 0.5-3 h) inhibits the growth and development of mycelia of R. solani and causes serious damage to the mycelial cell membrane^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2982993-88-2
분자량 389.18
화학식 C₁₁H₉Cl₂F₃N₄O₂S
SMILES

O=S(C1=C(C)NN=C1C(F)(F)F)(NNC2=CC=C(Cl)C=C2Cl)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chai JQ, et al. Potential Succinate Dehydrogenase Inhibitors Bearing a Novel Pyrazole-4-sulfonohydrazide Scaffold: Molecular Design, Antifungal Evaluation, and Action Mechanism. J Agric Food Chem. 2023 Jun 21;71(24):9266-9279. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass

Concentration

Volume

Molecular Weight

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Concentration _(start)

Volume _(start)

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Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- 제품 설명
- In Vitro
- In Vivo
Chemical Information
순도&문서
References

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