322 Results for "

linear

" in MedChemExpress (MCE) Product Catalog:
Products (322)

322 Results for "linear" in MCE Product Catalog:

Cat. No.: HY-W1048545D
Synonyms: Amine-PEG10000-Thiol hydrochloride
H2N-PEG10000-SH (Amine-PEG10000-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG10000-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
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Cat. No.: HY-W1048545E
Synonyms: Amine-PEG20000-Thiol hydrochloride
H2N-PEG20000-SH (Amine-PEG20000-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG20000-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
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Cat. No.: HY-W1048545H
Synonyms: Amine-PEG1000-Thiol hydrochloride
H2N-PEG1000-SH (Amine-PEG1000-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG1000-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
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Cat. No.: HY-W1048545I
Synonyms: Amine-PEG3400-Thiol hydrochloride
H2N-PEG3400-SH (Amine-PEG3400-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG3400-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
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Cat. No.: HY-W1048545J
Synonyms: Amine-PEG40000-Thiol hydrochloride
H2N-PEG40000-SH (Amine-PEG40000-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG40000-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
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Cat. No.: HY-W145522
CAS No.: 9057-02-7
Pullulan (Pullulan standard 5800) (Mw 362-480 kDa; Mn 100-200 kDa) is a class of orally active and water-soluble linear glucosic polysaccharide. Pullulan can be isolated from the polymorphic fungus Aureobasidium pullulans. Pullulan is composed of maltotriose repeating units linked by α-1,6 linkages and is an amorphous slime matter. Pullulan is widely used in food, environment, pharmaceutical, manufacturing, and electronics .
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Cat. No.: HY-Y1703
CAS No.: 148893-10-1
Research Areas:  

Others

HATU is a third-generation uronium salt peptide coupling reagent. HATU increases the rate of peptide coupling reactions, activates amino acids, promotes peptide bond formation in both solution-phase and solid-phase synthesis, and also facilitates peptide assembly, fragment coupling, and linear peptide cyclization. HATU can promote the N-acylation of chitosan to generate amide-linked cationic derivatives with a controllable degree of substitution. HATU is commonly used in amine acylation reactions .
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Cat. No.: HY-15582S
Auristatin E-d8 is the deuterium labeled Auristatin E (HY-15582). Auristatin E is a cytotoxic microtubule polymerization inhibitor with potent and selective antitumor activity. Auristatin E is a cytotoxin in antibody-drug conjugates (ADC). Auristatin E inhibits cell division by blocking the polymerisation of tubulin, promising for research in B-cell malignancies. Auristatin E, a synthetic analogue of the Dolastatin 10 (HY-15580), is linear peptides comprised of four amino acids .
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Cat. No.: HY-P0248F1
Research Areas:  

Others

Kemptide-FITC is a fluorescently labeled Kemptide (HY-P0248). Kemptide is a synthetic heptapeptide that acts as a specific substrate for cAMP-dependent protein kinase (PKA). Kemptide-FITC enables the quantification of PKA activity and can also indirectly determine cAMP concentrations through the activation of PKA in sperm insoluble fractions. Kemptide-FITC is applicable for kinase mobility shift assay (KiMSA), and its fluorescent signal shows a linear response with increasing peptide amount within a specific range on agarose gels .
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Cat. No.: HY-P11813
CAS No.: 160662-30-6
Target:  

Neurotensin Receptor

Research Areas:  

Neurological Disease

Cyclo (Arg-Lys-Pro-Tyr-Tle-Leu) is a cyclic peptide. Cyclo (Arg-Lys-Pro-Tyr-Tle-Leu) shows extremely low affinity for rat NTS1 expressed in cells (pKi < 4), whereas its semi-purified sample (Batch 2) exhibits moderate affinity for NTS1 (pKi = 5.83), a phenomenon attributed to contamination by an active linear peptide variant. Cyclo (Arg-Lys-Pro-Tyr-Tle-Leu) can be used in research on neurological diseases .
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Cat. No.: HY-W010922
CAS No.: 162558-25-0
Research Areas:  

Others

Fmoc-Dap (Boc)-OH is an amino acid derivative bearing the Fmoc protecting group. Fmoc-Dap (Boc)-OH supports Fmoc-based solid-phase peptide synthesis for the preparation of bicyclic tachykinin NK2 receptor antagonists .
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Cat. No.: HY-117387
CAS No.: 107572-73-6
Target:  

Endogenous Metabolite

Research Areas:  

Infection

BFE-37 is a yeast introduction with heat resistance activity. The survival rate change of BFE-37 after heating at 55 °C for 5 minutes was 6.53 log CFU/mL, showing its strong heat resistance in acidic orange juice. The dynamic behavior of BFE-37 at different temperatures showed a first-order logarithmic linear inactivation characteristic, which indicates its stability in heat treatment. The study of BFE-37 helps to understand the effect of mild heat treatment on juice and provide guidance for microbial control in the food industry .
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Cat. No.: HY-17466R
CAS No.: 808-26-4
Synonyms: Bonomycin (Standard); 6-Demethyl-6-deoxytetracycline (Standard)
Sancycline (Standard) is the analytical standard of Sancycline. This product is intended for research and analytical applications. Sancycline (6-Demethyl-6-deoxytetracycline) acts by reversibly binding to the 30 S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome a site similar to tetracycline (HY-A0107). Sancycline, four linearly fused six-membered rings with four stereocenters, is a rare semi-synthetic tetracycline (HY-A0107) prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin[1][2][3].
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Cat. No.: HY-W008598
CAS No.: 403-29-2
Synonyms: p-Fluorophenacyl bromide
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

2-Bromo-4'-fluoroacetophenone (p-Fluorophenacyl bromide) is a photoinducible DNA cleavage inducer.2-Bromo-4'-fluoroacetophenone generates fluorine-substituted phenyl radicals upon excitation and irradiation to cleave DNA, converting circular supercoiled DNA to circular relaxed and linear DNA forms.2-Bromo-4'-fluoroacetophenone exhibits concentration-dependent DNA cleaving activity.2-Bromo-4'-fluoroacetophenone can be used for the research of cancer .
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Cat. No.: HY-W099504
CAS No.: 111-70-6
Synonyms: n-Heptyl alcohol
1-Heptanol (n-Heptyl alcohol) is a linear primary fatty alcohol. 1-Heptanol selectively inhibits the activating phosphorylation of SAPK/JNK and reduces the phosphorylation level of IκB-α. 1-Heptanol increases plasma membrane fluidity, decreases membrane thermal stability, alters the coupling kinetics of STIM1-ORAI1, inhibits the production of ROS and LTC4, and induces the expression of HSP70. 1-Heptanol is used in the fragrance industry due to its pleasant odor .
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Cat. No.: HY-W1150738
CAS No.: 2809367-71-1
DDO-6513 is a STING molecular glue inhibitor with an IC50 of 1.93 μM. DDO-6513 selectively targets human STING but not murine STING, and exhibits a Kd value of 151 nM for human STING. DDO-6513 induces aberrant head-to-head STING oligomerization and disrupts the formation of normal signal-competent linear STING polymers. DDO-6513 inhibits STING-dependent downstream activation of TBK1 and IRF3, and suppresses the expression of proinflammatory cytokines. DDO-6513 can be used for research on STING-related autoinflammatory diseases .
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Cat. No.: HY-Y0004
CAS No.: 586-98-1
Research Areas:  

Inflammation/Immunology

2-Pyridinemethanol acts as a chelating auxiliary, co-catalyst and ligand, with pH-dependent coordination capacity for Cu (II) ions. 2-Pyridinemethanol can be used in combination with Acetylcholine (HY-B0282) and Pyridostigmine (HY-B0207A) for research related to obstructive arthropathy .
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Cat. No.: HY-Y0004R
CAS No.: 586-98-1
2-Pyridinemethanol (Standard) is the analytical standard of 2-Pyridinemethanol (HY-Y0004). This product is intended for research and analytical applications. 2-Pyridinemethanol acts as a chelating auxiliary, co-catalyst and ligand, with pH-dependent coordination capacity for Cu (II) ions. 2-Pyridinemethanol can be used in combination with Acetylcholine (HY-B0282) and Pyridostigmine (HY-B0207A) for research related to obstructive arthropathy .
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Cat. No.: HY-151640
CAS No.: 1021422-85-4
Target:  

ADC Linkers

Research Areas:  

Others

Fmoc-DAP-N3 is a click chemistry reagent containing an azide group. Fmoc-DAP-N3 is a short, linear spacer molecule with Fmoc protected amino function. Fmoc-DAP-N3 can be used in click conjugation and amid bond formation either with small molecules or for bioconjugation with proteins and antibodies . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Cat. No.: HY-D3400
Research Areas:  

Infection

CouCyCF3 is a fluorescent probe for bacterial cytoplasmic pH, with a pKa of 7.0. CouCyCF3 can be taken up by both Gram-positive and Gram-negative bacteria. Under acidic conditions, the fluorescence of CouCyCF3 in the red channel increases, while its fluorescence in the blue channel increases with elevated pH. A linear quantitative response is achieved via the I_red/I_blue ratio within the pH range of 5.0-7.5, with excitation/emission wavelengths of 445/472 nm (blue) and 640/708 nm (red). CouCyCF3 can be used for studies on bacterial acid tolerance and phagolysosome acidification .
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