111-70-6
Chemical Structure
1-Heptanol
Synonym(s): n-Heptyl alcohol
- CAS No.: 111-70-6
- Formula:C7H16O
- Molecular Weight:116.20
IUPAC Name: heptan-1-ol
InChIKey: BBMCTIGTTCKYKF-UHFFFAOYSA-N
SMILES: CCCCCCCO
Biological Activity: 1-Heptanol (n-Heptyl alcohol) is a linear primary fatty alcohol. 1-Heptanol selectively inhibits the activating phosphorylation of SAPK/JNK and reduces the phosphorylation level of IκB-α. 1-Heptanol increases plasma membrane fluidity, decreases membrane thermal stability, alters the coupling kinetics of STIM1-ORAI1, inhibits the production of ROS and LTC4, and induces the expression of HSP70. 1-Heptanol is used in the fragrance industry due to its pleasant odor[1][2][3].
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1-Heptanol | 99.50% | 1-Heptanol (n-Heptyl alcohol) is a linear primary fatty alcohol. 1-Heptanol selectively inhibits the activating phosphorylation of SAPK/JNK and reduces the phosphorylation level of IκB-α. 1-Heptanol increases plasma membrane fluidity, decreases membrane thermal stability, alters the coupling kinetics of STIM1-ORAI1, inhibits the production of ROS and LTC4, and induces the expression of HSP70. 1-Heptanol is used in the fragrance industry due to its pleasant odor. | ||||||||||||||||||||
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1-Heptanol-d15 | 99.0% | n-Heptyl Alcohol-d15 is the deuterium labeled 1-Heptanol. 1-Heptanol (n-Heptyl alcohol) is a linear primary fatty alcohol. 1-Heptanol selectively inhibits the activating phosphorylation of SAPK/JNK and reduces the phosphorylation level of IκB-α. 1-Heptanol increases plasma membrane fluidity, decreases membrane thermal stability, alters the coupling kinetics of STIM1-ORAI1, inhibits the production of ROS and LTC4, and induces the expression of HSP70. 1-Heptanol is used in the fragrance industry due to its pleasant odor. | ||||||||||||||||||||
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References
- [1]. Bugajev V, et al. Enhanced Membrane Fluidization and Cholesterol Displacement by 1-Heptanol Inhibit Mast Cell Effector Functions. Cells. 2023 Aug 15;12(16):2069. [Content Brief]
- [2]. Bonelli F, et al. Development and optimization of an ex vivo model of corneal epithelium damage with 1-heptanol: Investigating the influence of donor clinical parameters and MSC-sEV treatment on healing capacity. The ocular surface. 2025 Apr;36:224-236. [Content Brief]
- [3]. Dogan B, et al. Investigation on 1-heptanol as an oxygenated additive with diesel fuel for compression-ignition engine applications: An approach in terms of energy, exergy, exergoeconomic, enviroeconomic, and sustainability analyses. Fuel. 2020 Sep 1;275:117973.
