111-70-6
Chemical Structure
1-Heptanol
Synonym(s): n-Heptyl alcohol
- CAS No.: 111-70-6
- Formula:C7H16O
- Molecular Weight:116.20
IUPAC Name: heptan-1-ol
InChIKey: BBMCTIGTTCKYKF-UHFFFAOYSA-N
SMILES: CCCCCCCO
Biological Activity: 1-Heptanol (n-Heptyl alcohol) is a linear primary fatty alcohol. 1-Heptanol selectively inhibits the activating phosphorylation of SAPK/JNK and reduces the phosphorylation level of IκB-α. 1-Heptanol increases plasma membrane fluidity, decreases membrane thermal stability, alters the coupling kinetics of STIM1-ORAI1, inhibits the production of ROS and LTC4, and induces the expression of HSP70. 1-Heptanol is used in the fragrance industry due to its pleasant odor[1][2][3].
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1-Heptanol | 99.50% | 1-Heptanol (n-Heptyl alcohol) is a linear primary fatty alcohol. 1-Heptanol selectively inhibits the activating phosphorylation of SAPK/JNK and reduces the phosphorylation level of IκB-α. 1-Heptanol increases plasma membrane fluidity, decreases membrane thermal stability, alters the coupling kinetics of STIM1-ORAI1, inhibits the production of ROS and LTC4, and induces the expression of HSP70. 1-Heptanol is used in the fragrance industry due to its pleasant odor. | ||||||||||||||||||||
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1-Heptanol-d15 | 99.0% | 1-Heptanol-d15 (n-Heptyl alcohol-d15) is the deuterated-labeled 1-Heptanol (HY-W099504). 1-Heptanol (n-Heptyl alcohol) is a linear primary fatty alcohol. 1-Heptanol selectively inhibits the activating phosphorylation of SAPK/JNK and reduces the phosphorylation level of IκB-α. 1-Heptanol increases plasma membrane fluidity, decreases membrane thermal stability, alters the coupling kinetics of STIM1-ORAI1, inhibits the production of ROS and LTC4, and induces the expression of HSP70. 1-Heptanol is used in the fragrance industry due to its pleasant odor. | ||||||||||||||||||||
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Similarity Score 0.94
HY-W0320131-Octanol -
Similarity Score 0.93
HY-W0320221-Hexanol -
Similarity Score 0.90
HY-W008816RNonanol (Standard) -
Similarity Score 0.86
HY-Y1004R1-Decanol (Standard) -
Similarity Score 0.85
HY-W010505Hexane-1,6-diol -
Similarity Score 0.85
HY-416816-Chloro-1-hexanol -
Similarity Score 0.85
HY-W0079576-Amino-1-hexanol -
Similarity Score 0.85
HY-W0164556-Bromo-1-hexanol -
Similarity Score 0.85
HY-W4005746-Iodohexan-1-ol -
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References
- [1]. Bugajev V, et al. Enhanced Membrane Fluidization and Cholesterol Displacement by 1-Heptanol Inhibit Mast Cell Effector Functions. Cells. 2023 Aug 15;12(16):2069. [Content Brief]
- [2]. Bonelli F, et al. Development and optimization of an ex vivo model of corneal epithelium damage with 1-heptanol: Investigating the influence of donor clinical parameters and MSC-sEV treatment on healing capacity. The ocular surface. 2025 Apr;36:224-236. [Content Brief]
- [3]. Dogan B, et al. Investigation on 1-heptanol as an oxygenated additive with diesel fuel for compression-ignition engine applications: An approach in terms of energy, exergy, exergoeconomic, enviroeconomic, and sustainability analyses. Fuel. 2020 Sep 1;275:117973.