110 Results for "

ADC Toxin

" in MedChemExpress (MCE) Product Catalog:
Products (110)

110 Results for "ADC Toxin" in MCE Product Catalog:

Cat. No.: HY-132162A
CAS No.: 2740593-09-1
Target:  

ADC Payloads

Research Areas:  

Cancer

7-MAD-MDCPT hydrochloride, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs) .
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Cat. No.: HY-130978
Research Areas:  

Cancer

Duocarmycin DM, a DNA minor-groove alkylator, is an antibody agent conjugates (ADCs) toxin. Duocarmycin DM is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity .
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Cat. No.: HY-164088
CAS No.: 1644228-55-6
DBM-C5-VC-PAB-MMAE (Compound 3a) is a Drug-Linker conjugate for ADC. DBM-C5-VC-PAB-MMAE is composed of a linker C5-VC-PAB with a maleimide group DBM and an ADC toxin MMAE (HY-15162) .
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Cat. No.: HY-78932A
CAS No.: 2019182-02-4
Target:  

ADC Linkers

Research Areas:  

Cancer

Dap-NE hydrochloride is a dipeptide hydrochloride and a cleavable ADC Linker.Dap-NE hydrochloride can be used to connect Antibody and toxin molecules (Cytotoxin) to synthesize Antibody-Drug Conjugates (ADCs) .
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Cat. No.: HY-N2348
CAS No.: 309935-57-7
Tubulysin D is a highly cytotoxic anti-microtubule toxin (anti-microtubule toxins) that is synthesized as an ADC cytotoxin (ADC Cytotoxin). Tubulysin D can be isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. Tubulysin D displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the low nanomolar range. Tubulysin D inhibits microtubule/Tubulin polymerization and leads to cell cycle arrest and apoptosis .
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Cat. No.: HY-168317
CAS No.: 2983134-61-6
Research Areas:  

Cancer

LNK2-S is a conjugated compound of toxin molecule Exatecan (HY-13631) and Linker, which can be used to synthesize ADC molecule .
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Cat. No.: HY-41047
CAS No.: 228266-38-4
Target:  

Apoptosis

Research Areas:  

Cancer

Taltobulin intermediate-1 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis .
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Cat. No.: HY-41054
CAS No.: 610786-69-1
Target:  

Apoptosis

Research Areas:  

Cancer

Taltobulin intermediate-3 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis .
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Cat. No.: HY-128903
CAS No.: 2055896-83-6
Purity:  96.58%
Research Areas:  

Cancer

MC-Val-Cit-PAB-carfilzomib iodide is a conjugate of the ADC toxin molecule and the linker. MC-Val-Cit-PAB-carfilzomib iodide is formed by connecting the irreversible proteasome inhibitor Carfilzomib (HY-10455) and the ADC linker MC-Val-Cit-PAB (HY-78738).
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Cat. No.: HY-41045
CAS No.: 676487-35-7
Target:  

Apoptosis

Research Areas:  

Cancer

(Rac)-Taltobulin intermediate-1 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis .
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Cat. No.: HY-111965
CAS No.: 1822383-65-2
Synonyms: anti-EFNA4-ADC
PF-06647263 is an ADC targeting EFNA4, consisting of EFNA4 Antibody (HY-P991109), ADC toxin Calicheamicin (HY-19609) and a linker. PF-06647263 exhibits anti-tumor activity and induces significant tumor regression in TNBC xenografts .
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Cat. No.: HY-171489
CAS No.: 2028299-61-6
Research Areas:  

Cancer

Mal-VC-PAB-EDA-N-Ac-Calicheamicin is a Drug-Linker Conjugate for ADC with potent antitumor activity. Mal-VC-PAB-EDA-N-Ac-Calicheamicin consists of ADC toxin Calicheamicin (HY-19609) and a linker. Mal-VC-PAB-EDA-N-Ac-Calicheamicin can be used for synthesis of ADC, PF-06647263 (HY-111965) .
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Cat. No.: HY-128906
CAS No.: 1639793-15-9
Purity:  99.00%
Research Areas:  

Cancer

MC-Val-Cit-PAB-Retapamulin is a conjugate of a toxin molecule and a linker. It is formed by connecting the ribosomal protein synthesis inhibitor Retapamulin (HY-17010) and the ADC linker MC-Val-Cit-PAB (HY-78738).
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Cat. No.: HY-148380
CAS No.: 2679821-44-2
Research Areas:  

Cancer

Mal-PEG8-Phe-Lys-PAB-Exatecan (compound 15) is a agent-linker conjugate for ADC, composed of degradable linker Mal-PEG8-Phe-Lys-PAB and toxin molecule Exatecan (HY-13631) composition .
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Cat. No.: HY-122306
CAS No.: 82189-04-6
Synonyms: Mycotrienin II
Target:  

Antibiotic Bacterial

Research Areas:  

Infection Cancer

Ansatrienin B (Mycotrienin II) is an ansamycin antibiotic isolated from Streptomyces. Ansatrienin B is active against fungi and yeasts, but inactive against bacteria.Ansatrienin B displays antitumor antibiotic activity and can be used as an ADC Toxin .
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Cat. No.: HY-45171
CAS No.: 110351-93-4
Target:  

ADC Payloads

Research Areas:  

Cancer

Exatecan intermediate 12 is an intermediate for the synthesis of ADC toxin Exatecan (HY-13631) and can be used to prepare ADC compounds .
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Cat. No.: HY-158199
CAS No.: 2126749-95-7
Target:  

ADC Linkers

Research Areas:  

Cancer

BCN-HS-PEG2-bis(PNP) is a p-nitrophenyl ADC linker that can be used for further coupling of ADC toxins with peptide linkers. BCN-HS-PEG2-bis(PNP) can be combined with vc-PABC-MMAE (HY-15162) to form drug-linker conjugates for ADCs.
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Cat. No.: HY-N2347
CAS No.: 205304-88-7
Tubulysin C is a highly cytotoxic anti-microtubule toxin (anti-microtubule toxins) that is synthesized as an ADC cytotoxin (ADC Cytotoxin). Tubulysin C can be isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. Tubulysin C displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the low nanomolar range. Tubulysin C inhibits microtubule/Tubulin polymerization and leads to cell cycle arrest and apoptosis .
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Cat. No.: HY-N7050
CAS No.: 799822-08-5
Tubulysin G is a highly cytotoxic anti-microtubule toxin (anti-microtubule toxins) that is synthesized as an ADC cytotoxin (ADC Cytotoxin). Tubulysin G can be isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. Tubulysin G displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the low nanomolar range. Tubulysin G inhibits microtubule/tubulin polymerization and leads to cell cycle arrest and apoptosis .
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Cat. No.: HY-N7052
CAS No.: 799822-10-9
Tubulysin I is a highly cytotoxic anti-microtubule toxin (anti-microtubule toxins) that is synthesized as an ADC cytotoxin (ADC Cytotoxin). Tubulysin I can be isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. Tubulysin I displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the low nanomolar range. Tubulysin I inhibits microtubule/tubulin polymerization and leads to cell cycle arrest and apoptosis .
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