LNK2-S
Based on 1 Customer Validation
LNK2-S is a conjugated compound of toxin molecule Exatecan (HY-13631) and Linker, which can be used to synthesize ADC molecule.
For research use only. We do not sell to patients.
- Purity: 96.49%
- CAS No.: 2983134-61-6
- Formula: C87H112FN19O33
- Molecular Weight:1970.93
-
Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
All Drug-Linker Conjugates for ADC Isoforms
More
Biological Activity
Chemical Information
-
CAS No. 2983134-61-6
-
Appearance Solid
-
Molecular Weight 1970.93
-
Formula C87H112FN19O33
-
Color Light yellow to yellow
-
SMILES
O=C([C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC2=CC=C([C@@H](CNC(CC[C@H](NC(COCCOCCNC(CCN3C(C=CC3=O)=O)=O)=O)C(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)OC(N[C@H]4CCC5=C6C4=C(CN7C(C(COC([C@@]8(CC)O)=O)=C8C=C79)=O)C9=NC6=CC(F)=C5C)=O)C=C2[N+]([O-])=O)O1)O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (50.74 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (270 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.5074 mL | 2.5369 mL | 5.0737 mL | 12.6844 mL |
| 5 mM | 0.1015 mL | 0.5074 mL | 1.0147 mL | 2.5369 mL | |
| 10 mM | 0.0507 mL | 0.2537 mL | 0.5074 mL | 1.2684 mL | |
| 15 mM | 0.0338 mL | 0.1691 mL | 0.3382 mL | 0.8456 mL | |
| 20 mM | 0.0254 mL | 0.1268 mL | 0.2537 mL | 0.6342 mL | |
| 25 mM | 0.0203 mL | 0.1015 mL | 0.2029 mL | 0.5074 mL | |
| 30 mM | 0.0169 mL | 0.0846 mL | 0.1691 mL | 0.4228 mL | |
| 40 mM | 0.0127 mL | 0.0634 mL | 0.1268 mL | 0.3171 mL | |
| 50 mM | 0.0101 mL | 0.0507 mL | 0.1015 mL | 0.2537 mL |