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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
114 Results for "
CTLA4
" in MedChemExpress (MCE) Product Catalog:
Products (114)
114 Results for "CTLA4" in MCE Product Catalog:
Cat. No.: HY-RS03301
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Ctla4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ctla4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS03299
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CTLA4 Human Pre-designed siRNA Set A contains three designed siRNAs for CTLA4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P99709
CAS No.: 2118349-31-6
Synonyms: LY3300054
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Cat. No.: HY-P990703
CAS No.: 2649372-91-6
Synonyms: HBM-4003
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Cat. No.: HY-P99844
CAS No.: 2307144-64-3
Synonyms: ALPN-202; CD80 vIgD-Fc
Cat. No.: HY-179228
CAS No.: 1246964-08-8
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AN02 is a derivative of Curcumin (HY-N0005). AN02 inhibits the proliferation and clonogenicity, migration and invasion of ovarian cancer cells. AN02 dose-dependently upregulates the expression of APC and mediates the degradation of CTLA-4 through SMAD4. In the small xenograft model, AN02 significantly inhibits tumor growth and reverses the tumor immune-suppressive microenvironment. AN02, when combined with Ipilimumab (HY-P9901), can enhance efficacy and inhibit epithelial-mesenchymal transition. AN02 can be used for the study of ovarian cancer .
Cat. No.: HY-P99354
CAS No.: 2329669-78-3
Synonyms: Anti-Human CTLA4xLAG3; XmAb-22841; Pavunalimab
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Cat. No.: HY-P991566
CAS No.: 2983061-18-1
Cat. No.: HY-P991775
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Cat. No.: HY-P991827
Cat. No.: HY-P990848
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Cat. No.: HY-P990041
CAS No.: 2750031-14-0
Synonyms: ADG-116
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Cat. No.: HY-P990722
CAS No.: 2599198-80-6
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Cat. No.: HY-P990945
CAS No.: 2850355-80-3
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Cat. No.: HY-P990739
CAS No.: 2460399-39-5
Synonyms: BA-3071
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Evalstotug is an anti-CTLA4 human IgG1 κ monoclonal antibody . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
Cat. No.: HY-P990775
CAS No.: 2760549-50-4
Synonyms: XTX101
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Cat. No.: HY-P991139
CAS No.: 3014361-57-7
Synonyms: YH-001; C-17226
Cat. No.: HY-P990385
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Cat. No.: HY-L184
1,203 compounds
Gastric Cancer (GC) is one of the most common malignant tumors in the world, ranking fourth in mortality rate globally. Because the early symptoms of stomach neoplasm are usually not obvious, are diagnosed with gastric cancer at terminal stage, and the relative survival rate within 5 years is very low. With the further understanding of the molecular characteristics of stomach neoplasm, many therapeutic targets for gastric cancer have been identified, and molecular targeted therapies such as CTLA-4, HER2 and immune checkpoint inhibitors have made rapid progress. Although survival rates for patients with gastric neoplasm have improved over the past few decades, the prognosis is still worrying. Therefore, there is an urgent need for new drugs to treat gastric cancer.
MCE designs a unique collection of 1,203 small molecules with definite or potential anti-gastric cancer activity, which is an important tool for studying the pathological mechanism of stomach neoplasm and developing drugs for stomach neoplasm.
Cat. No.: HY-P991960
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
