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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
430 Results for "
IP
" in MedChemExpress (MCE) Product Catalog:
Products (430)
430 Results for "IP" in MCE Product Catalog:
5
5
5 Cited Publications
Cat. No.: HY-P7226
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL10; Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 10; Prev. SCYB10; Small-Inducible Cytokine B10; Prev. INP10; C-X-C Motif Chemokine 10; IP-10; Protein 10 From Interferon (Gamma)-Induced Cell Line; GIP-10; Interferon-Inducible Cytokine IP-1
Species:
Human
Source:
E. coli
5
5 Cited Publications
Target:
Research Areas:
3-Nitrocoumarin is an inhibitor for phospholipase C that blocks the generation of inositol triphosphate (IP3), thereby affecting the calcium signaling pathway .
4
4 Cited Publications
Cat. No.: HY-K0201A
MCE Anti-HA Magnetic Beads (1 μm) are used for immunoprecipitation (IP) of specific HA-tagged proteins expressed in bacterial and mammalian cells andin vitro expression systems. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
4
4
3
3
3 Cited Publications
Cat. No.: HY-B0584
CAS No.: 157283-68-6
Synonyms: Fluprostenol isopropyl ester; AL6221; Flu-IPr
Target:
Research Areas:
Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension .
3
3 Cited Publications
Synonyms: NS-304; ACT-293987
Target:
Research Areas:
Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin (PGI2) receptor (IP receptor).
3
3 Cited Publications
Target:
Research Areas:
KAG-308 is a potent selective and orally active agonist of EP4 receptor (a prostaglandin E2 receptor subtype), suppresses colitis and promotes histological mucosal healing, potently inhibits TNF-α production. KAG-308 shows a Ki and an EC50 of 2.57 nM and 17 nM for human EP4 receptor, respectively, more selective over EP1, EP2, EP3 and IP receptor .
3
2
2 Cited Publications
Cat. No.: HY-P3419
CAS No.: 929905-12-4
Research Areas:
2
Target:
Research Areas:
Treprostinil (UT-15C) diethanolamine is a potent EP2, DP1 and IP agonist with Ki values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1, EP4, EP3 and FP, respectively. Treprostinil (UT-15C) diethanolamine increases upregulation of cAMP toward maintaining homeostasis within the vasculature. Treprostinil (UT-15C) diethanolamine can result in vasodilatation of human pulmonary arteries .
2
2 Cited Publications
Synonyms: VU 0456810; CID 56642816
Target:
Research Areas:
ML 297 (VU 0456810) is a potent and selective GIRK1/2 activator, with an EC50 of 0.16 μM. ML 297 can cross the blood-brain barrier with brain-to-plasma ratio of 0.2 in mice model (i.p.). ML 297 is potential for the treatment of epilepsy .
2
Target:
Research Areas:
CpG ODN 10101 (ODN 10101; CPG 10101) is a selective agonist targeting TLR9, a synthetic oligodeoxynucleotide modified with phosphate thioester. CpG ODN 10101 activates B cells and plasmacytoid dendritic cells (pDCs), inducing the production of cytokines and chemokines such as interferon-IFN-α, interferon-inducible protein IP-10, and 2'5'-oligoadenylate synthase (2'5'-OAS), regulating innate immunity and promoting Th1 adaptive immune responses. CpG ODN 10101 also possesses antiviral properties and enhances vaccine immunogenicity, making it suitable as an immunomodulator and vaccine adjuvant for vaccine development in chronic hepatitis C and infectious diseases such as melioidosis, pertussis, and respiratory syncytial virus (RSV) .
2
Target:
Research Areas:
Nelotanserin is a potent 5-HT2A inverse agonist, a moderately potent 5-HT2C partial inverse agonist and a weak 5-HT2B inverse agonist, with IC50s of 1.7, 79, 791 nM in IP accumulation assays, respectively.
2
2 Cited Publications
Cat. No.: HY-18971
CAS No.: 1164462-05-8
Target:
Research Areas:
Neurological Disease Inflammation/Immunology Endocrinology Cancer
TG4-155 is a potent, brain-permeant and selective EP2 receptor antagonist with a Ki of 9.9 nM . TG4-155 shows low nanomolar antagonist activity against only EP2 and DP1 . TG4-155 has an EP2 Schild KB of 2.4 nM and displays 550-4750-fold selectivity for EP2 over EP1, EP3, EP4 and IP, but only 14-fold selectivity against the DP1 receptor .
1
1 Cited Publications
Cat. No.: HY-K0003
MCE IP Elution Buffer is a ready-to-use elution system specifically designed for IP/Co-IP experiments. It consists of an elution buffer and a matched neutralization buffer, enabling efficient and controlled elution of target proteins and ensuring compatibility with downstream analytical applications.
1
1 Cited Publications
Cat. No.: HY-P7227
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL10; Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 10; Prev. SCYB10; Small-Inducible Cytokine B10; Prev. INP10; C-X-C Motif Chemokine 10; IP-10; Protein 10 From Interferon (Gamma)-Induced Cell Line; GIP-10; Interferon-Inducible Cytokine IP-10; Mob-1; Chemokine (C-X-C Motif) Ligand 10; Crg-2; Gamma IP10; IFI10; Gamma-IP10; C7; C-X-C Motif Chemokine Ligand 10; 10 KDa Interferon Gamma-Induced Protein
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-K0249
MCE Anti-V5 Magnetic Beads are well suited for the detection and purification of V5-tagged fusion proteins, as well as for applications such as immunoprecipitation (IP) and co-immunoprecipitation (Co-IP). The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
