1. Metabolic Enzyme/Protease
  2. Phospholipase
  3. 3-Nitrocoumarin

3-Nitrocoumarin 

Cat. No.: HY-111919 Purity: 100%
Handling Instructions

3-Nitrocoumarin (3-NC) is a potent and selective Phospholipase C-γ (PLC-γ) inhibitor.

For research use only. We do not sell to patients.

3-Nitrocoumarin Chemical Structure

3-Nitrocoumarin Chemical Structure

CAS No. : 28448-04-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 88 In-stock
Estimated Time of Arrival: December 31
5 mg USD 80 In-stock
Estimated Time of Arrival: December 31
10 mg USD 140 In-stock
Estimated Time of Arrival: December 31
50 mg USD 490 In-stock
Estimated Time of Arrival: December 31
100 mg USD 860 Get quote
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

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Based on 1 publication(s) in Google Scholar

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Description

3-Nitrocoumarin (3-NC) is a potent and selective Phospholipase C-γ (PLC-γ) inhibitor[1].

IC50 & Target

PLC-γ[1].

Molecular Weight

191.14

Formula

C₉H₅NO₄

CAS No.

28448-04-6

SMILES

O=C1C([N+]([O-])=O)=CC2=CC=CC=C2O1

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (523.18 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.2318 mL 26.1588 mL 52.3177 mL
5 mM 1.0464 mL 5.2318 mL 10.4635 mL
10 mM 0.5232 mL 2.6159 mL 5.2318 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: 2.5 mg/mL (13.08 mM); Clear solution; Need ultrasonic

*All of the co-solvents are provided by MCE.
References
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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
3-Nitrocoumarin
Cat. No.:
HY-111919
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