28448-04-6
Chemical Structure
3-Nitrocoumarin
- CAS No.: 28448-04-6
- Formula:C9H5NO4
- Molecular Weight:191.14
IUPAC Name: 3-nitro-2H-chromen-2-one
InChIKey: YTCVPEZECJYZRK-UHFFFAOYSA-N
SMILES: O=C1C([N+]([O-])=O)=CC2=CC=CC=C2O1
Biological Activity: 3-Nitrocoumarin is an inhibitor for phospholipase C that blocks the generation of inositol triphosphate (IP3), thereby affecting the calcium signaling pathway[1][2].
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3-Nitrocoumarin | 100.0% | 3-Nitrocoumarin is an inhibitor for phospholipase C that blocks the generation of inositol triphosphate (IP3), thereby affecting the calcium signaling pathway. | ||||||||||||||||||||
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- [1]. Tisi R, et al., Phospholipase C is required for glucose-induced calcium influx in budding yeast. FEBS Lett. 2002 Jun 5;520(1-3):133-8. [Content Brief]
- [2]. Silverman-Gavrila LB, et al., An IP3-activated Ca2+ channel regulates fungal tip growth. J Cell Sci. 2002 Dec 15;115(Pt 24):5013-25. [Content Brief]
Keywords