3-Acetylcoumarin
Based on 1 Customer Validation
3-Acetylcoumarin (Compound 4) has acaricidal activity against Tetranychus cinnabarinus.
For research use only. We do not sell to patients.
- Purity: 97.0%
- CAS No.: 3949-36-8
- Formula: C11H8O3
- Molecular Weight:188.18
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Parasite Isoforms
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Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BTI-TN-5B1-4 | IC50 |
14.45 μM
Compound: 1
|
Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-tyramine after 15 mins by microplate fluorescence assay
Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-tyramine after 15 mins by microplate fluorescence assay
|
[PMID: 21872365] |
| SH-SY5Y | IC50 |
75 μM
Compound: AC
|
Cytotoxicity against human SH-SY5Y cells assessed as decrease in cell viability after 24 hrs by MTT assay
Cytotoxicity against human SH-SY5Y cells assessed as decrease in cell viability after 24 hrs by MTT assay
|
[PMID: 26232353] |
Chemical Information
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CAS No. 3949-36-8
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Appearance Solid
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Molecular Weight 188.18
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Formula C11H8O3
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Color Light yellow to yellow
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SMILES
O=C1C(C(C)=O)=CC2=CC=CC=C2O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (265.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.3141 mL | 26.5703 mL | 53.1406 mL | 132.8515 mL |
| 5 mM | 1.0628 mL | 5.3141 mL | 10.6281 mL | 26.5703 mL | |
| 10 mM | 0.5314 mL | 2.6570 mL | 5.3141 mL | 13.2852 mL | |
| 15 mM | 0.3543 mL | 1.7714 mL | 3.5427 mL | 8.8568 mL | |
| 20 mM | 0.2657 mL | 1.3285 mL | 2.6570 mL | 6.6426 mL | |
| 25 mM | 0.2126 mL | 1.0628 mL | 2.1256 mL | 5.3141 mL | |
| 30 mM | 0.1771 mL | 0.8857 mL | 1.7714 mL | 4.4284 mL | |
| 40 mM | 0.1329 mL | 0.6643 mL | 1.3285 mL | 3.3213 mL | |
| 50 mM | 0.1063 mL | 0.5314 mL | 1.0628 mL | 2.6570 mL | |
| 60 mM | 0.0886 mL | 0.4428 mL | 0.8857 mL | 2.2142 mL | |
| 80 mM | 0.0664 mL | 0.3321 mL | 0.6643 mL | 1.6606 mL | |
| 100 mM | 0.0531 mL | 0.2657 mL | 0.5314 mL | 1.3285 mL |