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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
Ref-1
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "Ref-1" in MCE Product Catalog:
Cat. No.: HY-P87296
Synonyms: Placental protein 5 antibody; PP5 antibody; Ref1 antibody; Retinal pigment epithelium cell factor 1 antibody; TFPI 2 antibody; TFPI-2 antibody; TFPI2 antibody; TFPI2 PEN antibody; TFPI2_HUMAN antibody; Tissue factor pathway inhibitor 2 antibody
Cat. No.: HY-120153
CAS No.: 1415030-17-9
Target:
Research Areas:
APX2014 is a Ref-1/APE1 inhibitor that inhibits Ref-1-induced transcription factor-DNA binding, thereby reducing the activation level of NF-κB and the expression of downstream pro-angiogenic targets. APX2014 blocks endothelial cell proliferation, lumen formation, migration and choroidal sprouting to exert anti-angiogenic activity. APX2014 activates the ISR pathway, promotes the death of pancreatic cancer cells and cancer-associated fibroblasts, and induces apoptosis in the absence of PRDX1. APX2014 inhibits the growth of pancreatic cancer spheroids, reduces the volume/weight of xenograft tumors, and decreases Ki-67 levels by targeting PRDX1. APX2014 can be used in research related to macular degeneration, retinopathy and pancreatic ductal adenocarcinoma [1] .
Cat. No.: HY-P705622
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TEAD1; Protein GT-IIC; Prev. TCF13; TCF-13; Prev. AA; TEAD-1; Transcriptional Enhancer Factor TEF-1; Atrophia Areata, Peripapillary Chorioretinal Degeneration; TEF-1; TEA Domain Family Member 1; TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor); Ref1; Transcriptional Enhancer Factor 1; TEF1; Transcription Factor 13; TEA Domain Transcription Factor 1; NTEF-1
Species:
Human
Source:
HEK293
Cat. No.: HY-RS21480
Target:
Research Areas:
Apex1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Apex1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
