76 Results for "

S228P

" in MedChemExpress (MCE) Product Catalog:
Products (76)

76 Results for "S228P" in MCE Product Catalog:

Cat. No.: HY-P991070

Target:  

TNF Receptor

Research Areas:  

Cancer

ADG-106 is a fully human agonistic monoclonal IgG4 antibody against CD137 (4-1BB). ADG-106 has the mechanism to activate CD137 via strong FcγRIIB-mediated crosslinking while antagonizing CD137 ligands. The isotype control for ADG-106 can refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P991675
CAS No.: 3031358-44-5

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Camtarkibart is an anti-IL4R IgG4κ type humanized antibody with immunomodulator activity. The recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P990752
CAS No.: 2657613-60-8
Synonyms: REGN-5678

Target:  

CD28

Research Areas:  

Inflammation/Immunology

Nezastomig is an anti-FOLH1/CD28 human IgG4 κ monoclonal antibody . Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
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Cat. No.: HY-P990975
CAS No.: 2894136-82-2

Research Areas:  

Inflammation/Immunology

HY-P990975 is an CSF2RB-targeting IgG4κ type human antibody, the recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P991062
Synonyms: Gensci-059

Target:  

CD47

Research Areas:  

Cancer

Gentulizumab (Gensci-059) is a humanized IgG4 antibody that targets CD47. Gentulizumab displays strong binding to CD47 in both human and monkey, and effectively inhibits the CD47-SIRPα interaction. Gentulizumab exhibits a potent antitumor activity. The isotype control for Gentulizumab can refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P99100A
CAS No.: 2556646-63-8
Synonyms: CLT-002 (Powder)

Research Areas:  

Cancer

Visugromab (CTL-002) (Powder) is a GDF-15 neutralizing IgG4 mAb. Visugromab (Powder) has synergistic anticancer activity with the anti-PD1 antibody Nivolumab (HY-P9903) and can effectively act on PD-1/PD-L1 relapsed/refractory metastatic solid tumors. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P990061
CAS No.: 2640981-19-5
Synonyms: JTX 8064
Polzastobart (JTX-8064) is a humanized IgG4 monoclonal antibody and LILRB2 (ILT4) antagonist. Polzastobart specifically binds to and antagonizes LILRB2, relieves ILT4-mediated myeloid immunosuppression, and promotes the polarization of macrophages from an M2-like phenotype to an M1-like phenotype. Polzastobart induces macrophage polarization, IFNγ signaling, and T cell inflammation-related pharmacodynamic responses in ex vivo human renal cancer, lung cancer, and head and neck cancer tissues. Polzastobart can be used in studies related to tumor-associated macrophages and tumor immunity. For the isotype control of Polzastobart, refer to: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P990696
CAS No.: 2647412-09-5
Synonyms: SHR-1222

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Resugosbart is an anti-SOST human IgG4 κ monoclonal antibody . Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
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Cat. No.: HY-P991121
CAS No.: 2988795-75-9
Baloncibart is a human IgG4K antibody targeting NPR1. The corresponding isotype control is: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P990702
CAS No.: 2642171-66-0
Synonyms: LVGN-3616

Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology

Pradusinstobart is an anti-PDCD1 human IgG4 κ monoclonal antibody . Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
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Cat. No.: HY-P990761
CAS No.: 2638480-59-6
Synonyms: JS-005

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Roconkibart is an anti-IL17A human IgG4 κ monoclonal antibody . Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
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Cat. No.: HY-P990949
CAS No.: 2851478-58-3
Synonyms: YYB-101; ABX101

Target:  

c-Met/HGFR

Research Areas:  

Inflammation/Immunology

HY-P990949 is an HGF-targeting IgG4κ type humanized antibody, the recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P990960
CAS No.: 2769742-99-4
Synonyms: AK-130

Research Areas:  

Inflammation/Immunology

HY-P990960 is an TIGIT-targeting IgG4κ type humanized antibody, the recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P990968
CAS No.: 2888563-73-1
Synonyms: LBL-007

Target:  

LAG-3

Research Areas:  

Inflammation/Immunology

HY-P990968 is an LAG3-targeting IgG4κ type human antibody, the recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P990976
CAS No.: 2786639-04-9
Synonyms: GLS-012
Target:  

LAG-3

Research Areas:  

Inflammation/Immunology

HY-P990976 is an LAG3-targeting IgG4κ type human antibody, the recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P990692
CAS No.: 2412587-62-1
Synonyms: JNJ-70218902; JNJ-902

Target:  

CD3

Research Areas:  

Inflammation/Immunology

Ciduvectamig is an anti-CD3E/TMEFF2 human IgG4 κ monoclonal antibody . Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
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Cat. No.: HY-P990910
CAS No.: 2833673-47-3
Synonyms: MG-K10

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

HY-P990910 is an IL4R-targeting IgG4κ type humanized antibody, the recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P990983
CAS No.: 2925270-26-2
Synonyms: SHR-1819

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

HY-P990983 is an IL4RA-targeting IgG4κ type humanized antibody, the recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P991009
CAS No.: 2928515-12-0
Synonyms: PT-199

Target:  

CD73

Research Areas:  

Inflammation/Immunology

HY-P991009 is an NT5E-targeting IgG4κ type human antibody, the recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P991727
CAS No.: 3036192-53-4
Synonyms: SAR-444881; BND-22
Zamristobart is an anti-LILRB1 (leukocyte immunoglobulin-like receptor B1) IgG4κ type humanized antibody with immunostimulant and antineoplastic activities. The recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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