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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
SOAT
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "SOAT" in MCE Product Catalog:
Cat. No.: HY-13215A
CAS No.: 166518-61-2
Synonyms: CI-1011 sodium; PD-148515 sodium
Target:
Research Areas:
Avasimibe sodium (CI-1011 sodium; PD-148515 sodium) is an orally active acyl coenzyme A-cholesterol acyltransferase (ACAT; also called SOAT)) inhibitor with IC50s of 24 and 9.2 µM for ACAT1 and ACAT2, respectively . Avasimibe sodium can be used for the research of prostate cancer .
Cat. No.: HY-121407A
CAS No.: 2180287-51-6
Target:
Research Areas:
(Rac)-Lateritin is an acyl-CoA:cholesterol acyltransferase (ACAT/SOAT) inhibitor, with IC50 values of 5.7 μM and 5.6 μM in rat liver, respectively. (Rac)-Lateritin exerts time-dependent irreversible enzyme inhibition that persists even after microsomal washing. (Rac)-Lateritin inhibits cholesterol ester formation in macrophages without altering triglyceride synthesis or other steps in oxidized low-density lipoprotein metabolism. (Rac)-Lateritin inhibits the growth of cancer cells, Gram-positive bacteria, and Candida albicans. (Rac)-Lateritin can be used in studies related to atherosclerosis, human solid tumors, mouse lymphocytic leukemia, as well as fungal and bacterial infections .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
