85 Results for "

sponge

" in MedChemExpress (MCE) Product Catalog:
Products (85)

85 Results for "sponge" in MCE Product Catalog:

  • Natural Products Recommended:
Cat. No.: HY-N10402
CAS No.: 1187954-93-3
Norbatzelladine L (Compound 2) is an inhibitor of the catalytic and functional activity of Pdr5p transporter. Norbatzelladine L inhibits Pdr5p ATPase activity with an IC50 of 3.8 µM. Norbatzelladine L shows antifungal, antiparasitic, antiviral, antibacterial and antitumoral activities .
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Cat. No.: HY-120985
CAS No.: 123000-02-2
Target:  

Calcium Channel

Research Areas:  

Neurological Disease

Xestospongins and araguspongins are marine natural products first isolated from Pacific basin sponges, and noted to have vasodilatory properties.1 Inositol phosphates (IP) are important signal transduction messengers acting via IP3 receptors to promote the mobilization of Ca2+ from intracellular stores.2 Araguspongin B antagonizes the calcium-releasing action of inositol 1,4,5-trisphosphate at the receptor level in cerebral microsomes, with an IC50 of 0.6 μM. It is nearly as potent as xestospongin C as an antagonist of the IP3 receptor.
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Cat. No.: HY-W834359
CAS No.: 219783-00-3
(±)-Longamide is a polycyclic bioactive metabolite isolated from sponges that has several bromopyrrole fragments, as well as a weak inhibitor of IDO1 .
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Cat. No.: HY-149712
CAS No.: 1001438-81-8
Target:  

ICMT

Research Areas:  

Cancer

Spermatinamine is a novel alkaloid with a bromotyrosyl-spermine-bromotyrosyl sequence, and a natural ICMT inhibitor. Spermatinamine can be isolated from the Australian sponge Pseudoceratina .
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Cat. No.: HY-N10305
CAS No.: 1042138-28-2
Clionamine B is an autophagy stimulating aminosteroid isolated from the sponge Cliona celata. Clionamine B strongly stimulates autophagy in human breast cancer MCF-7 cells .
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Cat. No.: HY-116436
CAS No.: 135383-64-1
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

Clathrodin is a marine alkaloid that can be isolated from sponges of the genus, Agelas. Clathrodin is a modulator of voltage-gated sodium (NaV) channels. Clathrodin is a sodium channel neurotoxin influencing sodium channel ionic conductance .
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Cat. No.: HY-123161
CAS No.: 1198588-57-6
JBIR-15 is a new aspochracin derivative. JBIR-15 is isolated from a sponge-derived fungus, Aspergillus sclerotiorum Huber Sp080903f04 .
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Cat. No.: HY-W268334
CAS No.: 17952-82-8
Research Areas:  

Infection

1,2,3,4-Tetrahydronorharman-1-one is a manzamine alkaloid with activity against infectious and tropical parasitic diseases from an Indonesian sponge .
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Cat. No.: HY-N10330
CAS No.: 959662-26-1
7-Hydroxyneolamellarin A is a natural product that could be derived from sponge Dendrilla nigra. 7-Hydroxyneolamellarin A is a potent hypoxia-inducible factor-1α (HIF-1α) inhibitor. 7-Hydroxyneolamellarin A attenuates the accumulation of hypoxia-inducible factor-1α (HIF-1α) protein and inhibits vascular epidermal growth factor (VEGF) transcriptional activity. 7-Hydroxyneolamellarin A can be used in research of cancer .
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Cat. No.: HY-113621B
CAS No.: 2757574-06-2
Target:  

Fluorescent Dye MMP

Research Areas:  

Cancer

Ageladine A dihydrochloride is an inhibitor of matrix metalloproteinase (MMP) isolated from the marine sponge Agelas nakamurai, possessing anti-angiogenic activity. Ageladine A dihydrochloride not only inhibits MMP-2 but also MMP-1, MMP-8, MMP-9, MMP-12, and MMP-13, with IC50 values of 4.65 μM, 2.79 μM, 907.12 nM, 1.83 μM, 767.57 nM, and 1.09 μM, respectively. Additionally, Ageladine A dihydrochloride is a pH-sensitive membrane-permeable dye that emits fluorescence in the blue-green range upon UV excitation, featuring a maximum absorption peak at 370 nm. Furthermore, Ageladine A dihydrochloride serves as a reliable and stable fluorescent pH sensor for detecting changes in intracellular pH values .
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Cat. No.: HY-123036
CAS No.: 73777-65-8
Target:  

Bacterial

Research Areas:  

Infection

Renierone is an antibacterial metabolite found in the sponge Reniera sp. .
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Cat. No.: HY-N7747
CAS No.: 79703-25-6
Sceptrin dihydrochloride is a compound isolated from the sea sponge Agelas sceptrum that is an antimicrobial agent .
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Cat. No.: HY-N10241
CAS No.: 346610-88-6
Hortein is a natural product from the fungus Hortaea werneckii associated with the sponge Aplysina aerophoba .
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Cat. No.: HY-N1032
CAS No.: 218780-16-6
(+)-12α-Hydroxyisodrimenin (compound 7) is a drimanic sesquiterpene that can be found in sponge Dysidea fusca .
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Cat. No.: HY-N1051
CAS No.: 160568-14-9
Zarzissine is a cytotoxic guanidine alkaloid that can be isolated from the Mediterranean sponge Anchinoe paupertas. Zarzissine shows antimicrobial and anticancer activities .
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Cat. No.: HY-N15283
CAS No.: 1141448-57-8
Baculiferins A is a DOPA-derived pyrrole alkaloid. Baculiferins A can be isolated from the Chinese marine sponge Iotrochota baculifera. Baculiferins A have anti-HIV activity .
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Cat. No.: HY-N15321
CAS No.: 1190954-39-2
Norselic acid B is a natural compound that can be isolated from the sponge Crella sp. collected in Antarctica. T. Norselic acid B is active against the Leishmania parasite .
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Cat. No.: HY-N15739
CAS No.: 2649683-40-7
(rel)-ent-Chromazonarol is the relative configuration of ent-Chromazonarol and is a sesquiterpene hydroquinone compound. (rel)-ent-Chromazonarol can be isolated from the sponge Disidea pallescens .
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Cat. No.: HY-127042
CAS No.: 122876-48-6
Synonyms: 6,7-Epoxy-LAT-A
6,7-Epoxy-latrunculin A can be isolated from the Red Sea sponge Negombata magnifica and is initially identified as an inhibitor of actin polymerization by its morphological effects .
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Cat. No.: HY-W411439
CAS No.: 7139-64-2
1-O-p-Coumaroyl-β-D-glucose can promote glucose uptake in HuH7 cells, and be be extracted from Luffa cylindrica (L.) Roem (sponge gourds) .
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