31 Results for "

Rotenone

" in MedChemExpress (MCE) Product Catalog:
Products (31)

31 Results for "Rotenone" in MCE Product Catalog:

Cat. No.: HY-173221
MJ210 is a modulator of the NF-κB and MAPK pathways with oral activity and the ability to penetrate the blood-brain barrier, and it exhibits neuroprotective activity. In vitro, 5 μM of MJ210 can increase the survival rate of SH-SY5Y cells treated with Rotenone (HY-B1756) to 81.9% and reduce the level of ROS, etc. In vivo, 5 mg/kg of MJ210 can improve the motor impairment in a rat model of Parkinson's disease. MJ210 can be used in the research of neurological diseases, such as Parkinson's disease .
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Cat. No.: HY-N18055
CAS No.: 3276-13-9
Derritol is a rotenone degradation product formed by the loss of C-6 and C-6a carbons from Rotenone (HY-B1756) .
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Cat. No.: HY-N11730
CAS No.: 36375-25-4
6',7'-Epoxyrotenone is a derivative and photodegradation product of Rotenone (HY-B1756), with an acute intraperitoneal LD50 of 7.2 mg/kg in mice .
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Cat. No.: HY-N11732
CAS No.: 36375-21-0
O-Demethylrotenone is a rotenone (HY-B1756) derivative and a photodegradation product of rotenone that induces acute intraperitoneal toxicity. The acute intraperitoneal LD50 of O-Demethylrotenone in Mus musculus is 8.0 mg/kg .
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Cat. No.: HY-101358R
CAS No.: 134865-70-6
Synonyms: AH-002 (Standard)
8-M-PDOT (Standard) is the analytical standard of 8-M-PDOT (HY-101358). This product is intended for research and analytical applications. 8-M-PDOT (AH-002) is a selective melatonin MT2 receptor agonist. 8-M-PDOT is 5.2-fold selective for MT2 over MT1 receptors. 8-M-PDOT binds human recombinant MT2 and MT2 receptors with pKi values of 8.23 and 8.95 respectively. 8-M-PDOT has anxiolytic-like activity .
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Cat. No.: HY-N11731
CAS No.: 4439-62-7
Rotenonone is a derivative of Rotenone (HY-B1756), with a LD50 of 0.68 μg/g against larvae of Spodoptera litura .
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Cat. No.: HY-121363
CAS No.: 492-87-5
Julocrotine is a naturally derived, orally active glutarimide alkaloid. Julocrotine alleviates rotenone-induced climbing impairment in Drosophila melanogaster and elevation of malondialdehyde levels in brain tissues, and restores the elevated mRNA levels of superoxide dismutase and catalase to normal. Julocrotine inhibits the growth of Leishmania amazonensis, induces its ultrastructural changes and reduces the number of amastigotes. Julocrotine can be used in research related to Parkinson's disease and cutaneous leishmaniasis .
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Cat. No.: HY-183437
CAS No.: 1522345-35-2
Target:  

Monoamine Oxidase

Research Areas:  

Neurological Disease

MAO-B-IN-57 is a selective MAO-B inhibitor with an IC50 of 41.38 nM against human MAO-B. MAO-B-IN-57 shows no significant in vitro cytotoxicity and can significantly increase the survival rate of PC12 cells damaged by 6-OHDA. MAO-B-IN-57 can be used in studies related to Parkinson's disease .
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Cat. No.: HY-B0886R
CAS No.: 305-33-9
Iproniazid (phosphate) (Standard) is the analytical standard of Iproniazid phosphate (HY-B0886). This product is intended for research and analytical applications. Iproniazid phosphate is an orally active, irreversible, non-selective monoamine oxidase (MAO) inhibitor. Iproniazid phosphate inhibits MAO activity and enhances Rotenone (HY-B1756)-induced Apoptosis. Iproniazid phosphate modulates neurotransmitter levels, affects neuronal function, induces hepatic necrosis, and interferes with the endocrine system. Iproniazid phosphate can be used in the research of depression, Parkinson's disease, and hepatotoxicity .
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Cat. No.: HY-187089
CAS No.: 58186-01-9
Target:  

Drug Derivative

Research Areas:  

Others

Idebenone impurity 1 is a short-chain naphthoquinone with an amino alcohol side chain. It is an impurity of Idebenone (HY-N0303) and exhibits no obvious biological activity .
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Cat. No.: HY-N7773
CAS No.: 577-24-2
Hibiscetin is an orally active anti-inflammatory, antioxidant, antihyperglycemic, hypolipidemic, hepatoprotective and neuroprotective agent. Hibiscetin reduces the levels of TNF-α, IL-1β and IL-6. Hibiscetin inhibits lipid peroxidation, reduces MDA levels, and induces the activities of antioxidant enzymes CAT, GSH and SOD. Hibiscetin lowers blood glucose, reverses reduced insulin levels, regulates adipokine levels, and reduces elevated AST and ALT levels. Hibiscetin alleviates Rotenone (HY-B1756)-induced akinesia and catalepsy, normalizes neurotransmitter levels, and modulates the activities of activated caspase 3 and BDNF. Hibiscetin can be used in the research of type 2 diabetes, Parkinson's disease and Huntington's disease .
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