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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5506 Results for "
Multivariate statistical analysis
" in MedChemExpress (MCE) Product Catalog:
Products (5506)
5506 Results for "Multivariate statistical analysis" in MCE Product Catalog:
Cat. No.: HY-118297R
CAS No.: 361154-30-5
Research Areas:
Ac4ManNAz (80% α isomer) (Standard) is the analytical standard of Ac4ManNAz (80% α isomer) (HY-118297). This product is intended for research and analytical applications. Ac4ManNAz is an azido-containing metabolic glycoprotein labeling reagent. Ac4ManNAz can be used to selectively modify proteins. Ac4ManNAz can be used in cell labeling, tracKing and proteomic analysis . Ac4ManNAz is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-156045B
CAS No.: 12774-36-6
Cat. No.: HY-156045C
CAS No.: 9041-36-5
Cat. No.: HY-183657
Target:
Research Areas:
GPR3 inverse agonist-1 is a GPR3 inverse agonist with low micromolar potency in conformational analysis. GPR3 inverse agonist-1 inhibits GPR3-dependent Gs activity in HEK293A cells with an EC50 of 250 nM, and exhibits an EC50 of 2 μM in cAMP assays. GPR3 inverse agonist-1 induces concentration-dependent changes in BRET signals in GPR3 conformational biosensors (EC50 = 5 μM), reduces basal Gs activity downstream of GPR3, and competes for binding sites with the GPR3 agonist DPI (HY-100965). GPR3 inverse agonist-1 can be used in research related to Alzheimer's disease .
Cat. No.: HY-183657A
Target:
Research Areas:
GPR3 inverse agonist-1 TFA is a GPR3 inverse agonist with low micromolar potency in conformational analysis. GPR3 inverse agonist-1 TFA inhibits GPR3-dependent Gs activity in HEK293A cells with an EC50 of 250 nM, and exhibits an EC50 of 2 μM in cAMP assays. GPR3 inverse agonist-1 TFA induces concentration-dependent BRET signal changes in GPR3 conformational biosensors (EC50 = 5 μM), reduces basal Gs activity downstream of GPR3, competes for binding sites with the GPR3 agonist DPI (HY-100965). GPR3 inverse agonist-1 TFA can be used in research related to Alzheimer's disease .
Cat. No.: HY-D0027R
CAS No.: 26093-31-2
Synonyms: Coumarin 120 (Standard); AMC (Standard)
Cat. No.: HY-D3181
Cat. No.: HY-P5429
CAS No.: 146064-85-9
Target:
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Cat. No.: HY-W013159R
CAS No.: 33430-61-4
Synonyms: 5′-dGMP disodium (Standard)
Category:
Cat. No.: HY-W127357
CAS No.: 126-53-4
Category:
Target:
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N-Lignoceroyl Taurine is an arachidonoyl amino acid and taurine conjugate with a fatty acid that can be isolated from bovine brain. N-Lignoceroyl Taurine is one of several novel taurine-conjugated fatty acids discovered during mass spectrometry lipidomic analysis of the brain and spinal cord of wild-type and fatty acid amide hydrolase (FAAH) knockout mice. N-Lignoceroyl Taurine levels were 23-26-fold higher in FAAH -/- mice compared to wild-type mice, suggesting that FAAH utilizes N-Lignoceroyl Taurine as a substrate. However, in vitro experiments with purified FAAH showed that N-Lignoceroyl Taurine was hydrolyzed 2,000-fold slower in FAAH compared to oleoylethanolamide. N-Acyl Taurines with polyunsaturated acyl chains can activate members of the transient receptor potential (TRP) calcium channel family, including TRPV1 and TRPV4.
Cat. No.: HY-170779
CAS No.: 3078291-78-5
DOTA-NI-FAPI-04 is a FAP inhibitor (IC50 = 7.44 nM). By integrating FAP targeting with hypoxia-sensitive groups (nitroimidazole), DOTA-NI-FAPI-04 significantly enhances tumor uptake and retention capabilities. DOTA-NI-FAPI-04 chelates metallic isotopes (such as 68Ga and 177Lu) through DOTA to produce radioactive probes ([68Ga]Ga/DOTA-NI-FAPI-04 and [177Lu]Lu/DOTA-NI-FAPI-04), which can be used for research in tumor diagnostics and therapeutic agents. DOTA-NI-FAPI-04 holds dual targeting potential in the fields of cancer imaging, tumor microenvironment analysis, and radionuclide therapy, particularly suitable for scenarios where the tumor stroma and hypoxic regions synergistically interact .
Cat. No.: HY-179551S
Cat. No.: HY-D0027S1
Synonyms: Coumarin 120-d4; AMC-d4
Cat. No.: HY-D3101
Target:
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Nile-TPA is a fluorescent probe for polarity detection, which can be used for lipid droplet targeting, cell polarity analysis, in vivo polarity imaging, and blood polarity monitoring in circulating tumor mouse models. The detection mechanism of Nile-TPA relies on the dual intramolecular charge transfer (ICT) effect generated by the electron-donating triphenylamine and Nile Red moieties and the electron-withdrawing carbonyl group; this probe emits strong red fluorescence in a low-polarity environment, and as polarity increases, the fluorescence intensity decreases and a red shift occurs due to changes in the excited-state dipole moment. In spectral tests, its excitation wavelength is 540 nm, and the emission wavelength varies in the range of 550-800 nm depending on solvent polarity; for cell, zebrafish and mouse imaging, Ex/Em = 561/570-620 nm, and for in vivo mouse imaging, Ex/Em = 560/620 nm .
Cat. No.: HY-DY1097
CAS No.: 107091-89-4
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
Cat. No.: HY-P5439
Cat. No.: HY-P5471
CAS No.: 204060-45-7
Synonyms: [Leu27]-Melan-A, MART-1 (26-35)
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Cat. No.: HY-P991980
Synonyms: H2Mab-141, H2Mab-19
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
