328 Results for "

CSF

" in MedChemExpress (MCE) Product Catalog:
Products (328)

328 Results for "CSF" in MCE Product Catalog:

  • Targets Recommended:
1
1 Cited Publications
Cat. No.: HY-P99259
CAS No.: 1613144-80-1
Synonyms: FPA 008; Anti-Human CSF1R Recombinant Antibody

Target:  

c-Fms

Research Areas:  

Inflammation/Immunology Cancer

Cabiralizumab (FPA 008) is an anti-CSF1R monoclonal antibody (MAb). Cabiralizumab enhances T cell infiltration and antitumor T cell immune responses. Cabiralizumab inhibits the activation of osteoclasts and blocks bone destruction, and can be used in the research of rheumatoid arthritis (RA). Cabiralizumab can combine with Nivolumab (HY-P9903) for lung cancer research .
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1
1 Cited Publications
Cat. No.: HY-P700137AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1; Macrophage Colony Stimulating Factor 1; Colony Stimulating Factor 1; Lanimostim; MCSF; MGC31930; Proteoglycan Macrophage Colony-Stimulating Factor; PG-M-CSF; Macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; CSF1-HERV-LTR71B Fusion Protein; Colo
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P701101
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1; Macrophage Colony Stimulating Factor 1; Colony Stimulating Factor 1; Lanimostim; MCSF; MGC31930; Proteoglycan Macrophage Colony-Stimulating Factor; PG-M-CSF; Macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; CSF1-HERV-LTR71B Fusion Protein; Colo
Species:  
Human
Source:  
CHO
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1
1 Cited Publications
Cat. No.: HY-P73831
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1; Macrophage Colony Stimulating Factor 1; Colony Stimulating Factor 1; Lanimostim; MCSF; MGC31930; Proteoglycan Macrophage Colony-Stimulating Factor; PG-M-CSF; Macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; CSF1-HERV-LTR71B Fusion Protein; Colo
Species:  
Cynomolgus
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-101768
CAS No.: 1802929-43-6
Purity:  99.78%
Target:  

FGFR c-Fms

Research Areas:  

Cancer

PRN1371 is a highly selective and potent FGFR1-4 and CSF1R inhibitor with IC50s of 0.6, 1.3, 4.1, 19.3 and 8.1 nM for FGFR1, FGFR2, FGFR3, FGFR4 and CSF1R, respectively .
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1
1 Cited Publications
Cat. No.: HY-P7184
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF2; Molgramostim; Colony Stimulating Factor 2; Molgramostin; GMCSF; CSF; Sargramostim; Granulocyte-Macrophage Colony Stimulating Factor; GM-CSF; Granulocyte Macrophage-Colony Stimulating Factor; Colony Stimulating Factor 2 (Granulocyte-Macrophage); Colo
Species:  
Rhesus Macaque
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P7068
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF3; Filgrastim; Prev. C17orf33; MGC45931; Prev. GCSF; Colony Stimulating Factor 3 Nirs Variant 1; Prev. G-CSF; Granulocyte Colony Stimulating Factor; Granulocyte Colony-Stimulating Factor; Granulocyte-Colony Stimulating Factor; Pluripoietin; Chromosome
Species:  
Mouse
Source:  
CHO
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1
1 Cited Publications
Cat. No.: HY-P7093A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF3; Filgrastim; Prev. C17orf33; MGC45931; Prev. GCSF; Colony Stimulating Factor 3 Nirs Variant 1; Prev. G-CSF; Granulocyte Colony Stimulating Factor; Granulocyte Colony-Stimulating Factor; Granulocyte-Colony Stimulating Factor; Pluripoietin; Chromosome
Species:  
Rat
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P73073
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF3; Filgrastim; Prev. C17orf33; MGC45931; Prev. GCSF; Colony Stimulating Factor 3 Nirs Variant 1; Prev. G-CSF; Granulocyte Colony Stimulating Factor; Granulocyte Colony-Stimulating Factor; Granulocyte-Colony Stimulating Factor; Pluripoietin; Chromosome
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P700083AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF3; Filgrastim; Prev. C17orf33; MGC45931; Prev. GCSF; Colony Stimulating Factor 3 Nirs Variant 1; Prev. G-CSF; Granulocyte Colony Stimulating Factor; Granulocyte Colony-Stimulating Factor; Granulocyte-Colony Stimulating Factor; Pluripoietin; Chromosome
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-132166
CAS No.: 2590556-80-0
Purity:  99.47%
Synonyms: M4205; IDRX-42
Target:  

c-Kit PDGFR c-Fms FLT3 Src

Research Areas:  

Cancer

Velzatinib (M4205) is a multi-target inhibitor for PDGFRB, PDGFRA, CSF1R, c-Kit, FLT3, and LCK, with an IC50s of 2.6, 50, 5.5, 44, 141 and 141 nM, respectively. Velzatinib exhibits antitumor efficacy in xenograft mouse models .
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1
1 Cited Publications
Cat. No.: HY-N0620
CAS No.: 102841-43-0
Mulberroside C is one of the main bioactive components in white mulberry (Morus alba L.). Mulberroside C exhibits antiplatelet, antiviral and neutrophil-regulating activities, and binds to EV-A71 VP1 with a Kd value of 1.289 nM. Mulberroside C reduces the phosphorylation level of ERK, promotes the phosphorylation of IP3RI at the Ser 1756 site, and decreases calcium influx and calcium mobilization. Mulberroside C inhibits the expression of P-selectin (P-selectin). Mulberroside C upregulates the cyclic nucleotide signaling pathway in human platelets. Mulberroside C binds to IL-23R, upregulates the expression of G-CSF, GM-CSF and RASGRP1, and activates the RAS/ERK signaling pathway. Mulberroside C promotes neutrophil maturation, accelerates the recovery of leukopenia, and enhances the antibacterial activity of neutrophils. Mulberroside C inhibits the replication of hepatitis C virus in replicon cells. Mulberroside C prevents the uncoating and genome release of EV-A71, and inhibits the synthesis of viral proteins and RNA. Mulberroside C can be used in studies related to thrombosis-mediated cardiovascular diseases, chemotherapy- and radiotherapy-induced leukopenia, hepatitis C virus infection, and hand, foot and mouth disease .
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1
1 Cited Publications
Cat. No.: HY-P71179
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: OLFM4; Olfactomedin-4; Olfactomedin 4; Olfactoimedin; GW112; Tiarin; OlfD; HGC-1; PDP4; HOLfD; GC1; OLM4; G-CSF-Stimulated Clone 1 Protein; BA209J19.1; Antiapoptotic Protein GW112; UNQ362
Species:  
Human
Source:  
HEK293
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1 Cited Publications
Cat. No.: HY-P10086
CAS No.: 1289375-12-7
Synonyms: Human TREM-1(213-221)
TREM-1 inhibitory peptide GF9 (Human TREM-1 (213-221)) is a TREM-1 inhibitor. TREM-1 inhibitory peptide GF9 blocks the TREM-1 signaling pathway via a ligand-independent mechanism, spontaneously inserts into the cell membrane to dissociate TREM-1 from DAP-12, and functions through the Signaling Chain Homooligomerization (SCHOOL) model. TREM-1 inhibitory peptide GF9 reduces the levels of TNFα, IL-1β, IL-6, and M-CSF. TREM-1 inhibitory peptide GF9 inhibits tumor growth, prolongs the survival of mice with pancreatic cancer models, ameliorates collagen-induced arthritis, and exerts protective effects on bone and cartilage simultaneously. TREM-1 inhibitory peptide GF9 can be used in research related to arthritis, pancreatic cancer, retinopathy, alcoholic liver disease, and liver cancer .
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Cat. No.: HY-P990125
Anti-Mouse (CSF1R/CD115) Antibody (AFS98) is an anti-mouse CSF1R IgG2a antibody inhibitor derived from rats. Anti-Mouse (CSF1R/CD115) Antibody (AFS98) inhibits M-CSF-dependent colony formation and cell growth by blocking the binding of M-CSF to its receptor. Anti-Mouse (CSF1R/CD115) Antibody (AFS98) can be used for the researches of inflammation, metabolic disease, cardiovascular disease and neurological disease, such as such as stroke, diabetes and arthritis .
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Cat. No.: HY-111787
CAS No.: 2271119-26-5
Purity:  99.93%
Synonyms: TPX-0022; CSF1R-IN-2
Target:  

Src c-Met/HGFR c-Fms

Research Areas:  

Cancer

Elzovantinib (TPX-0022) is an oral-active inhibitor of SRC, MET and c-FMS, with IC50 values of 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively .
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Cat. No.: HY-160842
CAS No.: 3024322-57-1
Target:  

c-Fms

Research Areas:  

Neurological Disease

CSF1R-IN-24 (Example 134) is an orally active CSF1R inhibitor. CSF1R-IN-24 significantly inhibits the survival of human ipSC-derived microglia (hiPSC-MG) .
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Cat. No.: HY-147615
CAS No.: 2361556-35-4
Purity:  98.75%
Target:  

c-Fms

Research Areas:  

Cancer

CSF1R-IN-12 (compound 1) is a potent inhibitor of CSF1R. Colony stimulating factor 1 (CSF-1, also known as macrophage colony stimulating factor, M-CSF) is an important growth factor that controls bone marrow progenitor cells, monocytes, macrophages, and giants. CSF1R-IN-12 has the potential for the research of cancer diseases .
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Cat. No.: HY-P990257

Target:  

c-Fms

Research Areas:  

Cancer

Anti-Mouse CSF1 Antibody (5A1) is a rat-derived anti-mouse CSF1 IgG1 κ type antibody inhibitor. Anti-Mouse CSF1 Antibody (5A1) can inhibit cells proliferation and macrophage-induced invasion. Anti-Mouse CSF1 Antibody (5A1) shows potent anti-tumor effect in various tumor models, such as neuroblastoma .
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Cat. No.: HY-P990384

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Anti-CSF3R/G-CSFR Antibody is a CHO-expressed human antibody that targets CSF3R/G-CSFR. Anti-CSF3R/G-CSFR Antibody contains huIgG4SP heavy chain and huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-CSF3R/G-CSFR Antibody can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).
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