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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
200 Results for "
RNA replication
" in MedChemExpress (MCE) Product Catalog:
Products (200)
200 Results for "RNA replication" in MCE Product Catalog:
Cat. No.: HY-N8533
CAS No.: 25387-67-1
Category:
Infection Alkaloids Pyrrole Alkaloids Quinoline Alkaloids Camptotheca acuminata Decne. Plants Nyssaceae Disease Research Fields
Target:
Research Areas:
ML336 is a Venezuelan equine encephalitis virus (VEEV) inhibitor with moderate passive blood-brain barrier permeability. ML336 inhibits viral RNA synthesis, virus-induced cytopathic effects and viral replication, reduces viral titers, and blocks the synthesis of VEEV genomic, subgenomic and template RNAs. ML336 can be used in studies related to VEEV infection .
Cat. No.: HY-131603
CAS No.: 143188-53-8
Synonyms: 3TCTP
Research Areas:
Lamivudine triphosphate (3TCTP) is a phosphorylated Lamivudine (HY-B0250) (a nucleoside analogue). Lamivudine triphosphate inhibits the reverse transcriptase of HIV or HBV viruses to block viral replication by chain termination. Lamivudine triphosphate is also an inhibitor of the RdRp activity of the NS5B subunit of the HCV. Lamivudine triphosphate can be incorporated into the nascent RNA by the SARS-CoV-2 RdRp, thus halting mutations in the nascent SARS-CoV-2 RNA .
Synonyms: LY122772
Target:
Research Areas:
Enviroxime (LY122772) is an antiviral compound that inhibits the replication of rhinoviruses and enteroviruses. Enviroxime blocks the replication of plus-strand viral RNA by targeting the viral 3A coding region. Enviroxime can be a useful tool for investigating the natural function of the 3A protein .
Cat. No.: HY-W011834R
CAS No.: 2140-72-9
Target:
Research Areas:
2'-O-Methylcytidine (Standard) is the analytical standard of 2'-O-Methylcytidine. This product is intended for research and analytical applications. 2'-O-Methylcytidine is an orally active 2'-substituted nucleoside as a inhibitor of HCV replication with antiviral activity. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate .
Cat. No.: HY-137697
CAS No.: 66004-77-1
Cat. No.: HY-W128400
CAS No.: 123402-21-1
Target:
Research Areas:
3′-Deoxy-3′-fluoroguanosine exhibits antiviral activity against tick-borne encephalitis virus (TBEV), through interaction with NS5B RdRp of HCV, resulting in suppression of viral RNA synthesis by disruption of further extension of the replicating viral RNA .
YH-53 is a potent 3CL pro inhibitor with Ki values of 6.3 nM, 34.7 nM for SARS-CoV-1 3CL pro and SARS-CoV-2 3CL pro, respectively. YH-53 strongly blocks the SARS-CoV-2 replication. YH-53 is a peptidomimetic compound with a unique benzothiazolyl ketone. YH-53 has the potential for COVID-19 research .
Cat. No.: HY-W011834S
CAS No.: 2653209-08-4
Cat. No.: HY-152081
CAS No.: 2499537-22-1
Target:
Research Areas:
DENV-IN-7, a flavone analog, is a dengue virus (DENV) inhibitor with an EC50 value of 70 nM. DENV-IN-7 has low toxicity against normal cell and anti-dengue activity .
Target:
Research Areas:
RdRP-IN-2 is a RNA dependent RNA polymerase (RdRp) inhibitor. RdRP-IN-2 significantly inhibits SARS-CoV-2 RdRp with an IC50 of 41.2 μM.RdRP-IN-2 also inhibits Feline coronavirus (FIPV) replication .
Cat. No.: HY-177817
Target:
Research Areas:
CL9 sodium, a RIG-I-specific RNA aptamer, activates signaling pathways for IFNβ produciton and efficiently blocks viral replication. RIG-I is a cytosolic receptor for non-self RNA that mediates immune responses against viral infections through IFNα/β prod
Cat. No.: HY-W555382
CAS No.: 55396-45-7
Synonyms: 2-Nonylquinolin-4(1H)-one
Category:
Alkaloids Ketones, Aldehydes, Acids Ruta graveolens Linn. Rutaceae Quinoline Alkaloids Plants
Target:
Cat. No.: HY-17470R
CAS No.: 50924-49-7
Synonyms: NSC 289637 (Standard); HE 69 (Standard)
Category:
Target:
Cat. No.: HY-148167
CAS No.: 622785-69-7
Target:
Research Areas:
2'-Deoxy-2'-fluoro-l-uridine is an L-nucleoside compound. 2'-Deoxy-2'-fluoro-l-uridine is a potent, selective viral RNA polymerase inhibitor, thereby inhibiting RNA virus replication .
Cat. No.: HY-W704973
CAS No.: 95740-26-4
Target:
Research Areas:
F-ara-EdU is a low-toxic, highly stable probe for DNA synthesis that is used as a marker for cell proliferation and DNA replication by binding to DNA or RNA in cells. F-ara-EdU can also be used to detect the rate of DNA synthesis within cells, as well as to study the mechanisms of DNA repair and damage .
Cat. No.: HY-N8188
CAS No.: 117824-04-1
Target:
Synonyms: NZ-4
Isothiafludine is an orally active non-nucleosidic anti-HBV compound. Isothiafludine inhibits hepatitis B virus replication by blocking pregenomic RNA encapsidation .
Cat. No.: HY-I0515
CAS No.: 1496552-51-2
Sofosbuvir impurity K, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir. Sofosbuvir (PSI-7977) is an inhibitor of HCV RNA replication, demonstrates potent anti-hepatitis C virus activity.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
