208 Results for "

extend

" in MedChemExpress (MCE) Product Catalog:
Products (208)

208 Results for "extend" in MCE Product Catalog:

Cat. No.: HY-137694B
Purity:  99.94%
ddTTP trisodium solution (100 mM) is a DNA polymerase γ inhibitor, with Ki values of 0.05 μM and 0.4 μM against bovine testicular DNA polymerase γ. ddTTP trisodium solution (100 mM) can be incorporated into DNA to cause termination of the extended DNA strand. ddTTP trisodium solution (100 mM) can be used in the research of HIV infection .
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Cat. No.: HY-125366
CAS No.: 1432499-49-4
Purity:  ≥90.0%
Target:  

FAP

Research Areas:  

Metabolic Disease

ARI-3099 is an oral fibroblast activation protein (FAP) inhibitor. ARI-3099 specifically inhibits the proteolytic activity of FAP and blocks the cleavage of human FGF-21 between residues P171 and S172. ARI-3099 extends the half-life of circulating human FGF-21 in mice. ARI-3099 can be used in the research of type 2 diabetes and metabolic disorders .
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Cat. No.: HY-117685
CAS No.: 141195-77-9
Purity:  99.79%
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Cefovecin sodium is an extended-spectrum semisynthetic cephalosporin and bactericidal agent. Cefovecin sodium exerts potent antibacterial activity against multiple bacterial. Cefovecin sodium can be used for the research of bacterial infection .
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Cat. No.: HY-B0810AR
CAS No.: 32887-03-9
Synonyms: FL-1039 hydrochloride (Standard)
Research Areas:  

Infection

Pivmecillinam (hydrochloride) (Standard) is the analytical standard of Pivmecillinam (hydrochloride). This product is intended for research and analytical applications. Pivmecillinam hydrochloride (FL-1039 hydrochloride) is an orally active proagent of mecillinam, an extended-spectrum penicillin antibiotic.
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Cat. No.: HY-157485
CAS No.: 339287-36-4
Purity:  99.99%
Target:  

Potassium Channel

Research Areas:  

Others

Ebio1 is a selective voltage-gated potassium channel KCNQ2 activator. Ebio1 activates KCNQ2 by generating an extended channel gate with greater conductance at a saturation voltage (+50 mV) .
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Cat. No.: HY-155528
CAS No.: 412008-21-0
Purity:  99.89%
Target:  

Others

Research Areas:  

Others

O4I4 (compound 23) is a OCT4-inducing compound with metabolical stability. O4I4 extends lifespan in Caenorhabditis elegans and Drosophila. O4I4 can be used for regenerative medicine and rejuvenation research .
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Cat. No.: HY-117948
CAS No.: 1560968-49-1
Research Areas:  

Cancer

ML399 is a Menin-MLL1 protein-protein interaction inhibitor with an IC50 of 90 nM. ML399 inhibits the proliferation of transformed mouse bone marrow cells. ML399 binds to the hERG potassium channel, exhibits superior in vitro physicochemical, drug metabolism and pharmacokinetic (DMPK) parameters, and has an extended half-life in rodents. ML399 can be used for research on acute myeloid leukemia and acute lymphoblastic leukemia .
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Cat. No.: HY-P99875
CAS No.: 2252477-42-0
Synonyms: BIVV-001; Altuvoct

Target:  

Inhibitory Antibodies

Research Areas:  

Cardiovascular Disease

Efanesoctocog alfa is a B domain-deleted single-chain Factor VIII (FVIII) connected to D'D3 domain of von Willebrand Factor (vWF). Efanesoctocog alfa has an extended half-life. Efanesoctocog alfa can be used for the study of inherited hemophilia A .
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Cat. No.: HY-16752R
CAS No.: 1174018-99-5
Synonyms: MK-7655 (Standard)
Research Areas:  

Infection

Relebactam (Standard) is the analytical standard of Relebactam. This product is intended for research and analytical applications. Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases and KPC) and class C (AmpC) enzymes. Relebactam shows antibacterial activity .
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Cat. No.: HY-164546
CAS No.: 2248552-84-1
Target:  

STAT Apoptosis

Research Areas:  

Cancer

WB436B is a highly selective STAT3 inhibitor. WB436B can selectively inhibit STAT3-Tyr705 phosphorylation and the expression of STAT3 target genes, showing cytotoxic effects on pancreatic cancer cells and inducing apoptosis. WB436B can suppress tumor growth and metastasis in pancreatic cancer mouse models, extending the survival of tumor-bearing mice .
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Cat. No.: HY-B0810
CAS No.: 32886-97-8
Synonyms: FL-1039
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Pivmecillinam (FL-1039) is an orally active proagent of mecillinam, an extended-spectrum penicillin antibiotic.
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Cat. No.: HY-B1466A
CAS No.: 51481-65-3
Synonyms: BAY-f 1353
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Mezlocillin (BAY-f 1353) is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin is active against both gram-negative and gram-positive bacteria. Mezlocillin can be used in bacterial infection research .
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Cat. No.: HY-162269
CAS No.: 3041005-21-1
Target:  

NAMPT

Research Areas:  

Inflammation/Immunology

Nampt activator-5 is a NAMPT activator with a KD value of 6.19 μM. Nampt activator-5 activates the rate-limiting enzyme in NAD + biosynthesis and promotes NAD + production. Nampt activator-5 delays the senescence process of senescent hepatocytes, extends the lifespan of *Caenorhabditis elegans*, and alleviates age-related dysfunction and abnormal biomarkers in naturally aged mice. Nampt activator-5 can be used in aging research .
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Cat. No.: HY-139805
CAS No.: 34787-01-4
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Ticarcillin is a semisynthetic, extended-spectrum, carboxypenicillin antibacterial agent, and is active against gram-positive cocci, including streptococci and staphylococci. Ticarcillin is also effective against most gram-negative organisms, including Pseudomonas aeruginosa. Ticarcillin can be used in lower respiratory tract infections, skin and skin structure infections, urinary tract infections, and intraabdominal infections research .
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Cat. No.: HY-A0035
CAS No.: 106560-14-9
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Faropenem is a potent and orally active beta-lactam antibiotic. Faropenem demonstrates broad-spectrum in vitro antimicrobial activity against many gram-positive and -negative aerobes and anaerobes. Faropenem is resistant to hydrolysis by nearly all beta-lactamases, including extended-spectrum beta-lactamases and AmpC beta-lactamases. Faropenem is developed as an oral proagent, faropenem medoxomil, for the research of respiratory tract infections .
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Cat. No.: HY-N12514
CAS No.: 19275-51-5
Cyclomulberrin is a extended flavonoid that shows inhibition of arachidonic acid (AA)- and collagen-induced platelet aggregation, with IC50 value of 128.2 μM .
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Cat. No.: HY-P2937
CAS No.: 9012-90-2
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

DNA polymerase is a polymerase agent targeting DNA templates. DNA polymerase catalyzes the polymerization of deoxyribonucleotides (dNTPs) to extend DNA strands with high fidelity and processivity. DNA polymerase is promising for research of cancers .
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Cat. No.: HY-W783829
CAS No.: 10018-93-6
Synonyms: Hex-2-trans-enoyl-CoA
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

(2E)-Hexenoyl-CoA (Hex-2-trans-enoyl-CoA) is an intermediate in fatty acid metabolism. (2E)-Hexenoyl-CoA undergoes reductive carboxylation to yield butylmalonyl-CoA .
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Cat. No.: HY-N15389
CAS No.: 155-38-4
Noformicin has inhibitory effect on mumps virus and Newcastle disease virus in chicken embryo. Noformicin also extended the survival of mice infected with swine, influenza A (PR8) and influenza B (Lee) viruses .
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Cat. No.: HY-P990966
CAS No.: 2793441-31-1
Synonyms: JR-142

Target:  

GHR IGF-1R

Research Areas:  

Others

Redalsomatropin alfa (JR-142) is a recombinant long-acting growth hormone. Redalsomatropin alfa extends its half-life through fusion with modified serum albumin. Redalsomatropin alfa is well-tolerated and can maintain IGF-1 levels. Redalsomatropin alfa can be used in research related to growth hormone deficiency .
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