105 Results for "

max

" in MedChemExpress (MCE) Product Catalog:
Products (105)

105 Results for "max" in MCE Product Catalog:

Cat. No.: HY-159756B
Target:  

c-Myc

Research Areas:  

Cancer

KI-MS2-008 is a selective Max binder. KI-MS2-008 results in the stabilization of Max homodimers and the attenuation of Myc. KI-MS2-008 has anticancer activity against Myc-dependent cancer .
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Cat. No.: HY-125636
CAS No.: 313987-85-8
Target:  

c-Myc

Research Areas:  

Cancer

Mycro1 is an inhibitor of c-Myc/Max dimer and DNA binding, with an IC50 value of 30 μM for the inhibition of Myc/Max DNA binding activity. Mycro1 can inhibit c-myc-dependent cell proliferation, gene transcription and oncogenic transformation .
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Cat. No.: HY-N6878
CAS No.: 12672-45-6
Cauloside D is a triterpene glycoside isolated from Caulophyllum robustum Max. Cauloside D exerts anti-inflammatory effects through the inhibition of expression of iNOS and proinflammatory cytokines .
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Cat. No.: HY-131024
Synonyms: JF549, Tetrazine
Janelia Fluor 549, Tetrazine (JF549, Tetrazine) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor fluorescent dyes can be chemically conjugated to the specific HaloTag substrate (a chloroalkane ligand) to form a fluorescent ligand, rather than binding directly to the HaloTag protein itself. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
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Cat. No.: HY-131023
Synonyms: JF549, Maleimide TFA
Janelia Fluor 549, Maleimide TFA (JF549, Maleimide TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor fluorescent dyes can be chemically conjugated to the specific HaloTag substrate (a chloroalkane ligand) to form a fluorescent ligand, rather than binding directly to the HaloTag protein itself. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
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Cat. No.: HY-178045
CAS No.: 3109265-41-7
Target:  

c-Myc

Research Areas:  

Cancer

MYC-IN-4 is a MYC inhibitor. MYC-IN-4 impairs MYC/MAX protein-protein interaction (IC50 = 3.06 μM). MYC-IN-4 inhibits MYC-aberrant PC-3 prostate cancer cells with an IC50 of 0.440 μM. MYC-IN-4 demonstrates potent antitumor efficacy in FVB mice bearing Myc-CaP prostate tumor allografts. MYC-IN-4 can be used for the study of prostate cancer .
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Cat. No.: HY-N5072R
CAS No.: 17817-31-1
Synonyms: 4',6,7-Trihydroxyisoflavone (Standard)
Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities. Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity . Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1) . Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes .
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Cat. No.: HY-145723A
CAS No.: 2388506-51-0
Target:  

FLT3 FGFR

Research Areas:  

Inflammation/Immunology Cancer

MAX-40279 hydrochloride is a dual and orally active inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 hydrochloride is also effective against the FLT3 mutants such as FLT3 D835Y, suggesting that it can overcome resistance to Quizartinib (HY-13001) and Sorafenib (HY-10201). MAX-40279 hydrochloride inhibits NDRG1 phosphorylation at Ser330 and suppresses endothelial-to-mesenchymal transition (EndMT). MAX-40279 hydrochloride can be used for the research of acute myelogenous leukemia (AML) .
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Cat. No.: HY-RS08177
Research Areas:  

Others

MAX Human Pre-designed siRNA Set A contains three designed siRNAs for MAX gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17397
Research Areas:  

Others

Max Mouse Pre-designed siRNA Set A contains three designed siRNAs for Max gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-N4074
CAS No.: 137705-39-6
6"-O-Malonylglycitin is an isoflavone glycoside that can be isolated from Glycine max .
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Cat. No.: HY-136784
CAS No.: 663625-18-1
Rhod-2 potassium is a cell impermeant, red fluorescent calcium indicator. Rhod-2 potassium exhibits a significant shift in fluorescence intensity upon calcium binding (ex max=549 nm; calcium-free v. ex/em max=552/581 nm; calcium-bound). Unlike the UV-excitable indicators Fura-2 and Indo-1 (HY-D0121), there is no accompanying spectral shift .
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Cat. No.: HY-136784A
Rhod-2 sodium is a cell impermeant, red fluorescent calcium indicator. Rhod-2 sodium exhibits a significant shift in fluorescence intensity upon calcium binding (ex max=549 nm; calcium-free v. ex/em max=552/581 nm; calcium-bound). Unlike the UV-excitable indicators Fura-2 and Indo-1 (HY-D0121), there is no accompanying spectral shift .
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Cat. No.: HY-P10253
CAS No.: 118026-35-0
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Homo-phytochelatin is heavy metal chelator presented in legumes .
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Cat. No.: HY-N12273
CAS No.: 117230-34-9
Synonyms: Acetyl-soyasaponin A5
Soyasaponin Ae (Acetyl-soyasaponin A5) can be isolated from the seeds of Glycine max MERRILL .
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Cat. No.: HY-115839A
CAS No.: 33774-52-6
Synonyms: Detajmium bitartrate; Tachmalcor
Target:  

Sodium Channel

Research Areas:  

Cardiovascular Disease

Detajmium (L-tartrate) is an antiarrhythmic compound. Detajmium has effect on V max in both dog ventricular muscle and Purkinje fibers was frequency dependent .
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Cat. No.: HY-N6919
CAS No.: 20853-58-1
Cauloside C is a triterpene glycoside isolated from Caulophyllum robustum Max. Cauloside C exerts anti-inflammatory effects through the inhibition of expression of iNOS and proinflammatory cytokines .
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Cat. No.: HY-N1228
CAS No.: 114297-20-0
Soyacerebroside I is a glycosphingolipid, together with Soyacerebroside II, which can be isolated from the seeds of Glycine max Merrill (Leguminosae). Soyacerebroside II shows ionophoretic activity for Ca 2+ .
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Cat. No.: HY-115796
CAS No.: 1926222-30-1
Target:  

mGluR

Research Areas:  

Others

VU0477886 is a metabotropic glutamate receptor subtype 4 (mGlu4) positive allosteric modulator with potent activating activity on mGlu4 (EC50 = 95nM, 89% Glu Max), good pharmacokinetic characteristics (brain: plasma Kp = 1.3), and significant therapeutic efficacy in Parkinson's disease models.
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Cat. No.: HY-W800769
CAS No.: 2669097-24-7
BP Fluor 532 Azide Plus is a fluroescent agent with a terminal azide group. The fluroescent compound has a max absorption at 532 nm and emission at 554 nm. The BP Fluor 532 Azide Plus was designed with a copper-chelating system within its structure, enabling the formation of strong, active copper complexes that act as both reactant and catalyst in CuAAC reactions.
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