313987-85-8
313987-85-8
Chemical Structure
Mycro1
- CAS No.: 313987-85-8
- Formula:C20H15F3N4O2S
- Molecular Weight:432.42
IUPAC Name: N-(4-methoxybenzyl)-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
InChIKey: AARUNXNNAZIAQK-UHFFFAOYSA-N
SMILES: O=C(NCC1=CC=C(C=C1)OC)C2=NN3C(C(F)(F)F)=CC(C4=CC=CS4)=NC3=C2
Biological Activity: Mycro1 is an inhibitor of c-Myc/Max dimer and DNA binding, with an IC50 value of 30 μM for the inhibition of Myc/Max DNA binding activity. Mycro1 can inhibit c-myc-dependent cell proliferation, gene transcription and oncogenic transformation[1].
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Mycro1 | Mycro1 is an inhibitor of c-Myc/Max dimer and DNA binding, with an IC50 value of 30 μM for the inhibition of Myc/Max DNA binding activity. Mycro1 can inhibit c-myc-dependent cell proliferation, gene transcription and oncogenic transformation. | |||||||||||||||||||||
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References
Keywords
