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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
75 Results for "
GLUT1
" in MedChemExpress (MCE) Product Catalog:
Products (75)
75 Results for "GLUT1" in MCE Product Catalog:
Cat. No.: HY-138976
CAS No.: 2226614-88-4
Research Areas:
NV-5440 (Compound I-120) is an mTORC1 inhibitor and glucose transporter inhibitor. NV-5440 targets GLUT-1, -2, -3, and -4, and shows no activity against GLUT-5. NV-5440 inhibits glucose uptake [1] .
Cat. No.: HY-RS13157
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SLC2A1 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC2A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26023
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Slc1a3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc1a3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS13159
Target:
Research Areas:
Slc2a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc2a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-100017R
CAS No.: 1799753-84-6
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BAY-876 (Standard) is the analytical standard of BAY-876 (HY-100017). This product is intended for research and analytical applications. BAY-876, a chemical probe, is an orally active and selective glucose transporter 1 (GLUT1) inhibitor with an IC50 of 2 nM. BAY-876 is >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 is also a potent blocker of glycolytic metabolism and ovarian cancer growth. In addition, BAY-876 can induce the formation of disulfide bonds in actin cytoskeletal proteins, leading to the occurrence of cellular disulfidptosis [1] .
Cat. No.: HY-RS19528
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Research Areas:
Slc1a3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc1a3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-129165
CAS No.: 618361-63-0
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ZINC08383544 is a PKM2 activator with anti-tumor activity. ZINC08383544 binds to the dimer-dimer interface of PKM2, promotes tetramer formation, blocks nuclear translocation, inhibits the expression of glycolysis-related genes such as GLUT1, and reduces T cell-mediated inflammatory responses. ZINC08383544 can be used in cancer-related research such as cervical cancer [1].
Cat. No.: HY-189274
CAS No.: 3128930-57-1
Target:
HIF/HIF Prolyl-Hydroxylase VEGFR GLUT Reactive Oxygen Species (ROS) Biochemical Assay Reagents
Research Areas:
HIF-1α stabilizer-1 is a HIF-1α stabilizer and iron chelator. HIF-1α stabilizer-1 induces HIF-dependent transcription and upregulates VEGFA and GLUT1 expression without directly binding to PHD1-3. HIF-1α stabilizer-1 inhibits hyperglycemia-induced ROS accumulation. HIF-1α stabilizer-1 promotes cell migration. HIF-1α stabilizer-1 accelerates wound closure and improves tissue remodeling by enhancing neovascularization and collagen deposition. HIF-1α stabilizer-1 lacks antibacterial activity against P. aeruginosa. HIF-1α stabilizer-1 can be used for research on diabetic wounds [1].
Cat. No.: HY-182250
CAS No.: 2505339-87-5
Research Areas:
BR103354 is an orally active, selective fibroblast activation protein (FAP) inhibitor with an IC50 value of 14 nM against hFAP. BR103354 restores the levels of phosphorylated ERK and Glut1 that are reduced by co-treatment with hFGF21 and FAP, decreases non-fasting blood glucose concentrations, improves glucose tolerance, and reduces hepatic triglyceride content. BR103354 ameliorates hepatic steatosis and hepatic fibrosis. BR103354 can be used in the research of type 2 diabetes and non-alcoholic steatohepatitis [1].
Cat. No.: HY-D3311
Cat. No.: HY-RS13158
Target:
Research Areas:
Slc2a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc2a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-180805
CAS No.: 2679261-30-2
Target:
Research Areas:
HK2-IN-3 is a selective HK2 inhibitor with a human IC50 of 0.0564 μM (56.4 nM). HK2-IN-3 induces mitophagy in oral squamous cell carcinoma cells. HK2-IN-3 exerts anti-cancer activity in oral squamous cell carcinoma cells. HK2-IN-3 can be used for the research of oral squamous cell carcinoma [1].
Cat. No.: HY-N21978
CAS No.: 247031-40-9
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
