594 Results for "

Integrin

" in MedChemExpress (MCE) Product Catalog:
Products (594)

594 Results for "Integrin" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-113439S
CAS No.: 2525175-25-9
Purity:  ≥98.0%
Target:  

Apoptosis

12-HETE-d8 is the deuterium labeled 12-HETE. 12-HETE, a major metabolic product of arachidonic acid using 12-LOX catalysis, inhibits cell apoptosis in a dose-dependent manner. 12-HETE promotes the activation and nuclear translocation of NF-κB through the integrin-linked kinase (ILK) pathway .12-HETE has both anti-thrombotic and pro-thrombotic effects . 12-HETE is a neuromodulator .
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2
2 Cited Publications
Cat. No.: HY-N0031
CAS No.: 104777-68-6
Plantamajoside is an orally active phenylpropanoid glycoside. Plantamajoside can be isolated from Plantago asiatica L.(Plantaginaceae). Plantamajoside inactivates NF-κB, PI3K/akt, induces Apoptosis, and improves Autophagy. Plantamajoside regulates MAPK, integrin-linked kinase/c-Src. Plantamajoside inhibits multiple cancers, improves lung and kidney damage. Plantamajoside has neuroprotective and anti-inflammatory effects .
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1
1 Cited Publications
Cat. No.: HY-P83377
Synonyms: AI1H; Integrin beta-6

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-P77721A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGAV; Integrin, Alpha V (Vitronectin Receptor, Alpha Polypeptide, Antigen CD51); Prev. MSK8; Vitronectin Receptor; Prev. VNRA; Integrin AlphaVbeta3; Prev. VTNR; Integrin, Alpha V; Vitronectin Receptor Subunit Alpha; CD51 Antigen; Integrin Alpha-V; IDNDC
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P77719
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ITGAV; Integrin, Alpha V (Vitronectin Receptor, Alpha Polypeptide, Antigen CD51); Prev. MSK8; Vitronectin Receptor; Prev. VNRA; Integrin AlphaVbeta3; Prev. VTNR; Integrin, Alpha V; Vitronectin Receptor Subunit Alpha; CD51 Antigen; Integrin Alpha-V; IDNDC
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P77720
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ITGAV; Integrin, Alpha V (Vitronectin Receptor, Alpha Polypeptide, Antigen CD51); Prev. MSK8; Vitronectin Receptor; Prev. VNRA; Integrin AlphaVbeta3; Prev. VTNR; Integrin, Alpha V; Vitronectin Receptor Subunit Alpha; CD51 Antigen; Integrin Alpha-V; IDNDC
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P700762
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGAV; Integrin, Alpha V (Vitronectin Receptor, Alpha Polypeptide, Antigen CD51); Prev. MSK8; Vitronectin Receptor; Prev. VNRA; Integrin AlphaVbeta3; Prev. VTNR; Integrin, Alpha V; Vitronectin Receptor Subunit Alpha; CD51 Antigen; Integrin Alpha-V; IDNDC
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P73870
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ITGA6; CD49f; Integrin Subunit Alpha 6; Very Late Activation Protein 6; VLA-6; Integrin, Alpha 6; CD49 Antigen-Like Family Member F; Integrin Alpha6B; Integrin Alpha-6; CD49f Antigen; ITGA6A; JEB6; ITGA6B; ITGB4; GP150; Integrin Subunit Beta 4; Integrin,
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P77718
Purity:  ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: ITGA5; Integrin Alpha-F; Prev. FNRA; CDNA FLJ50382, Moderately Similar To Integrin Alpha-5; CD49e; Very Late Activation Protein 5, Alpha Subunit; Integrin, Alpha 5 (Fibronectin Receptor, Alpha Polypeptide); Fibronectin Receptor, Alpha Subunit; Fibronectin
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P86388
Synonyms: ITGB1; FNRB; MDF2; MSK12; Integrin beta-1; Fibronectin receptor subunit beta; VLA-4 subunit beta; CD antigen CD29

Host:  

Rabbit

Application:  

WB, IHC-P, ELISA, IF-Tissue

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-P77716
Purity:  ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: ITGA2B; Platelet Fibrinogen Receptor, Alpha Subunit; Prev. GP2B; Platelet Glycoprotein IIb; GPIIb; AlphaIIb Protein; Integrin Alpha-IIb; Glycoprotein IIb; PPP1R93; CD41 Antigen; CD41B; BDPLT16; CD41; BDPLT2; Integrin, Alpha 2b (Platelet Glycoprotein IIb O
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P83275
Synonyms: ITGA6; CD49 antigen-like family member F; VLA-6; CD49f

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-P700752
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGA2; Alpha 2 Integrin; Prev. CD49B; Very Late Activation Protein 2 Receptor, Alpha-2 Subunit; GPIa; Very Late Activation Receptor Alpha-2 Subunit; CD49 Antigen-Like Family Member B; Human Platelet Alloantigen System 5; Platelet Membrane Glycoprotein Ia
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P990203

Target:  

Integrin

Research Areas:  

Inflammation/Immunology

Anti-Mouse LPAM-1/Integrin α4β7 Antibody (DATK32) is a rat-derived anti-LPAM-1/Integrin α4β7 IgG2a, κ type antibody inhibitor. Anti-Mouse LPAM-1/Integrin α4β7 Antibody (DATK32) specifically reacts with both chains of the α4β7 heterodimer and blocks the adhesion to immobilized mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Anti-Mouse LPAM-1/Integrin α4β7 Antibody (DATK32) suppresses the proliferation and cytokine secretion of CD8+ T cells. Anti-Mouse LPAM-1/Integrin α4β7 Antibody (DATK32) decreases Peyer’s patches and follicular B cells in mice. Anti-Mouse LPAM-1/Integrin α4β7 Antibody (DATK32) can be used for the researches of inflammation, such as ulcerative colitis .
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1
1 Cited Publications
Cat. No.: HY-P5133
CAS No.: 1259384-47-8
Synonyms: SSTN92-119
Target:  

Integrin

Research Areas:  

Cancer

Synstatin (92-119) is an inhibitor of αvβ3/αvβ5 integrins and IGF1R with anti-angiogenic, anti-proliferative, antioxidant and anti-tumor activities. Synstatin (92-119) competitively blocks the capture of αvβ3/αvβ5 integrins and IGF1R by syndecan-1, disrupts the formation of the syndecan-1 : integrin : IGF1R ternary complex, inhibits integrin activation and talin-mediated signaling pathways, and blocks VEGF-induced angiogenesis. Synstatin (92-119) is applicable to research related to cancer and hepatocellular carcinoma .
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1
1 Cited Publications
Cat. No.: HY-W008859
CAS No.: 67-30-1
Synonyms: Tetraiodothyroacetic acid; 3,3',5,5'-Tetraiodothyroacetic acid
Tetrac (Tetraiodothyroacetic acid), a derivative of L-thyroxine (T4), is a thyrointegrin receptor antagonist. Tetrac blocks the actions of T4 and 3,5,3'-triiodo-L-thyronine (T3) at the cell surface receptor for thyroid hormone on integrin αvβ3. Tetra has anti-angiogenic and anti-tumor activities .
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1
1 Cited Publications
Cat. No.: HY-P3448
CAS No.: 2580154-02-3
Synonyms: CEND-1; iRGD; LSTA1
Research Areas:  

Cancer

Certepetide (CEND-1) is a bifunctional cyclic peptide (a.k.a. iRGD). Certepetide is a tumor-penetrating enhancer via RGD motif interaction with alphav-integrins and via activating NRP-1, and transforms the solid tumor microenvironment into a temporary agent conduit. Certepetide accumulates in tumors, and is used in the research of pancreatic cancer and other solid tumors .
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1
1 Cited Publications
Cat. No.: HY-P2267
CAS No.: 1155866-55-9
Target:  

Integrin

Research Areas:  

Others

LDV is a non-fluorescent analog of LDV-FITC. LDV is a α4β1 integrin (VLA-4) ligand, and binds α4β1 integrin in leukemia cells .
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1
1 Cited Publications
Cat. No.: HY-P83653
Synonyms: p150/95 Integrin alpha chain; Leu M5; SLEB6; ITGAX; CD11c; p150; Myeloid membrane antigen alpha subunit; Leukocyte surface antigen p150 95 alpha subunit; Integrin alpha-X; Integrin alpha X

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP

Reactivity:  

Human

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1
1 Cited Publications
Cat. No.: HY-P72917
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD47; Antigen Identified By Monoclonal Antibody 1D8; Prev. MER6; Integrin-Associated Protein; Leukocyte Surface Antigen CD47; Rh-Related Antigen; IAP; CD47 Glycoprotein; Antigenic Surface Determinant Protein OA3; Integrin-Associated Signal Transducer; OA3; CD47 Antigen; CD47 Antigen (Rh-Related Antigen, Integrin-Associated Signal Transducer); Protein MER6; CD47 Molecule; Integrin Associated Protein
Species:  
Human
Source:  
HEK293
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