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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
121 Results for "
polyamine
" in MedChemExpress (MCE) Product Catalog:
Products (121)
121 Results for "polyamine" in MCE Product Catalog:
Cat. No.: HY-W680647
CAS No.: 99207-33-7
Target:
Research Areas:
MDL 72527 free base is a potent polyamine oxidase (PAO) inhibitor. MDL 72527 free base shows a lysosomotropic effect. MDL 72527 shows neuroprotective effects .
Cat. No.: HY-151148
CAS No.: 2355349-41-4
Trypanothione synthetase-IN-1 (Compound 1) is a competitive Leishmania infantum trypanothione synthetase (TryS) inhibitor with an IC50 of 14.8 μM when triamine spermidine is as polyamine S .
Cat. No.: HY-151150
CAS No.: 3033799-60-6
Trypanothione synthetase-IN-2 (Compound 3) is a competitive Leishmania infantum trypanothione synthetase (TryS) inhibitor with an IC50 of 5.4 μM when triamine spermidine is as polyamine S .
Cat. No.: HY-113056AS1
Cat. No.: HY-W190917
CAS No.: 2250433-79-3
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N1, N4-Bisazidospermine bistosylate is a spermine linker containing two azide groups. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Spermidine is a polyamine that modulates various cellular activities like cellular development and differentiation, stability of DNA, and apoptosis.
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Synthalin hydrochloride is a K+ channel blocker with neuronal excitability modulating activity. Synthalin hydrochloride has an effect on NMDA-mediated depolarization, possibly through receptor-mediated modulation of L-glutamate and serotonin (5-HT). The use of Synthalin hydrochloride can enhance the understanding of changes in membrane potential of different neurons and help study the role of polyamines in neuronal excitability .
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Cat. No.: HY-N0455AR
CAS No.: 1119-34-2
Synonyms: (S)-(+)-Arginine hydrochloride (Standard)
Category:
Cat. No.: HY-W190905
CAS No.: 177213-61-5
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N4, N9-di-Boc-spermine is a spermine linker containing two a Boc-protected amino groups and two amine groups. The Boc groups can be deprotected under mild acidic conditions to form the free amine. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Spermidine is a polyamine that modulates various cellular activities like cellular development and differentiation, stability of DNA, and apoptosis.
Cat. No.: HY-129912S
CAS No.: 2597353-33-6
Cat. No.: HY-179870
CAS No.: 142970-49-8
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Chenodeoxycholyl-cadaverine is a polyamine bile amidate.
Cat. No.: HY-179871
CAS No.: 142970-48-7
Chenodeoxycholyl-putrescine is a polyamine bile amidate.
Cat. No.: HY-179872
CAS No.: 142970-25-0
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Cholyl-cadaverine is a polyamine bile amidate.
Cat. No.: HY-179874
CAS No.: 142970-24-9
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Cholyl-putrescine is a polyamine bile amidate.
Cat. No.: HY-167938
CAS No.: 949933-50-0
Synonyms: (E/Z)-CGC-11047
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(E/Z)-PG-11047 ((E/Z)-CGC-11047) is a polyamine analog with potential application in lung cancer inhibition. (E/Z)-PG-11047 effectively inhibited the growth of non-small cell and small cell lung cancer cells. (E/Z)-PG-11047 exhibits significant biochemical effects in non-small cell lung cancer cells, resulting in significant downregulation of polyamine synthetase activity. (E/Z)-PG-11047 induces polyamine metabolism, resulting in a significant reduction in polyamine levels .
Cat. No.: HY-P701854
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PMF1; Est1p-Like Protein B (EST1B); polyamine Modulated Factor 1; PMF-1; polyamine-Modulated Factor 1
Species:
Human
Source:
E. coli
Cat. No.: HY-187370
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Research Areas:
YDH-704 is a PAK1/HDAC10 inhibitor, with IC50 values of 0.05 μM and 0.02 μM against human targets, respectively. YDH-704 blocks PAK1-mediated oncogenic signaling pathways, inhibits the proliferation and migration of tumor cells, suppresses the epigenetic regulatory function of HDAC10, downregulates PD-L1 expression, and regulates polyamine metabolism. YDH-704 reduces MDSC/Treg infiltration, enhances the infiltration and activation of CD8 + T cells, and inhibits tumor growth and lung metastasis. YDH-704 can be used for research on triple-negative breast cancer .
Cat. No.: HY-183624
CAS No.: 1258530-99-2
Trimer44NMe is a polyamine transport inhibitor (PTI). Trimer44NMe inhibits the polyamine transport of putrescine (Put), spermidine (Spd), and spermine (Spm). Trimer44NMe can be used for research of Pancreatic ductal adenocarcinoma (PDAC) .
Cat. No.: HY-P701855
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PMF1; Est1p-Like Protein B (EST1B); polyamine Modulated Factor 1; PMF-1; polyamine-Modulated Factor 1
Species:
Human
Source:
E. coli
Cat. No.: HY-179873
CAS No.: 136533-45-4
Target:
Research Areas:
Cholyl-1,3-diaminopropane is a polyamine bile amidate.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
