125 Results for "

Sec

" in MedChemExpress (MCE) Product Catalog:
Products (125)

125 Results for "Sec" in MCE Product Catalog:

  • Targets Recommended:
Art. -Nr.: HY-P89078A
Synonyms: PRELID4A; Sec14L

Host:  

Mouse

Application:  

IHC-P

Reactivity:  

Human, Mouse, Rat

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Art. -Nr.: HY-P88221
Synonyms: ARNO; CTS18; CTS18.1; cytohesin-2; PSCD2; PSCD2L; Sec7L; Sec7p-L; Sec7p-like

Host:  

Mouse

Application:  

IHC-P

Reactivity:  

Human, Mouse, Rat

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Art. -Nr.: HY-P88221A
Synonyms: ARNO; CTS18; CTS18.1; cytohesin-2; PSCD2; PSCD2L; Sec7L; Sec7p-L; Sec7p-like

Host:  

Mouse

Application:  

IHC-P

Reactivity:  

Human, Mouse, Rat

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Art. -Nr.: HY-P89140
Synonyms: 1810012E07Rik; Sec11L1; sid2895; SPC18; SPCS4A

Host:  

Mouse

Application:  

IHC-P

Reactivity:  

Human, Mouse, Rat

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Art. -Nr.: HY-182690
CAS. Nr.: 1883356-12-4
Target:  

HIV

Forschungsgebiete:  

Infection

CK147 is a Sec61α translocase inhibitor that blocks the co-translational translocation of proteins by binding to and inhibiting the Sec61 protein translocation channel on the endoplasmic reticulum membrane. CK147 exhibits potent CD4 downregulation activity with an IC50 of 0.04 µM. CK147 prevents HIV entry into host cells and shows significant cytotoxicity. CK147 can be used in studies related to HIV infection .
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Art. -Nr.: HY-P83484
Synonyms: CLCRP2

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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Art. -Nr.: HY-P89140A
Synonyms: 1810012E07Rik; Sec11L1; sid2895; SPC18; SPCS4A

Host:  

Mouse

Application:  

IHC-P

Reactivity:  

Human, Mouse, Rat

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Art. -Nr.: HY-P83584
Synonyms: BCL2 adenovirus E1B 19kD interacting protein 1; BNIP1; Nip1; Sec20; Sec20L; Transformation-related gene 8 protein; TRG8; Vesicle transport protein Sec20

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

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Art. -Nr.: HY-P83484A
Synonyms: CLCRP2

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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Art. -Nr.: HY-P88184
Synonyms: CDA-II; CDAII; CDAN2; HEMPAS

Host:  

Mouse

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

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Art. -Nr.: HY-P811817
Synonyms: Sec13L, SEH1, SEH1L, Nucleoporin SEH1, GATOR2 complex protein SEH1, Nup107-160 subcomplex subunit SEH1, Sec13-like protein

Host:  

Rabbit

Application:  

WB, FC, ICC/IF, IHC-P

Reactivity:  

Human, Mouse, Rat

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Art. -Nr.: HY-P88184A
Synonyms: CDA-II; CDAII; CDAN2; HEMPAS

Host:  

Mouse

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

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Art. -Nr.: HY-P10466
CAS. Nr.: 2377734-91-1
KZR-8445, a cyclic depsipeptide, is a client-selective Sec61 inhibitor. KZR-8445 binds to the fully opened Sec61 lateral gate, blocks lumenal plug domain access, stabilizes lateral gate helices, traps select signal peptides, and disrupts secretory and membrane protein biogenesis. KZR-8445 inhibits pro-inflammatory cytokine secretion in primary immune cells. KZR-8445 inhibits SARS-CoV-2 replication, virus-induced cytotoxicity, and spike protein biogenesis. KZR-8445 blocks disease progression in a mouse model of rheumatoid arthritis. KZR-8445 can be used for the researches of rheumatoid arthritis and SARS-CoV-2 infection .
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Art. -Nr.: HY-P10466A
KZR-8445 TFA, a cyclic depsipeptide, is a client-selective Sec61 inhibitor. KZR-8445 TFA binds to the fully opened Sec61 lateral gate, blocks lumenal plug domain access, stabilizes lateral gate helices, traps select signal peptides, and disrupts secretory and membrane protein biogenesis. KZR-8445 TFA inhibits pro-inflammatory cytokine secretion in primary immune cells. KZR-8445 TFA inhibits SARS-CoV-2 replication, virus-induced cytotoxicity, and spike protein biogenesis. KZR-8445 TFA blocks disease progression in a mouse model of rheumatoid arthritis. KZR-8445 TFA can be used for the researches of rheumatoid arthritis and SARS-CoV-2 infection .
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Art. -Nr.: HY-P3987A
Target:  

Sec61

Forschungsgebiete:  

Cancer

Cotransin TFA is a cyclic ester peptide and a Sec61 translocator binder with signal sequence-selective activity to inhibit co-translational protein translocation. Cotransin TFA inhibits the biogenesis of a subset of secretory and membrane proteins in a signal peptide-dependent manner. Cotransin TFA is applicable for cancer-related research .
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Art. -Nr.: HY-P811817A
Synonyms: Sec13L, SEH1, SEH1L, Nucleoporin SEH1, GATOR2 complex protein SEH1, Nup107-160 subcomplex subunit SEH1, Sec13-like protein

Host:  

Rabbit

Application:  

WB, FC, ICC/IF, IHC-P

Reactivity:  

Human, Mouse, Rat

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Art. -Nr.: HY-P71465
Reinheit:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Enterotoxin type C-2; Sec2; entC2
Species:  
Staphylococcus aureus
Source:  
E. coli
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Art. -Nr.: HY-P87068
Synonyms: Alpha-tocopherol-associated protein (TAP hTAP) Squalene transfer protein Supernatant protein factor (SPF)

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Art. -Nr.: HY-111549R
CAS. Nr.: 369631-68-5
Forschungsgebiete:  

Cancer

Bragsin1 (Standard) is the analytical standard of Bragsin1 (HY-111549). This product is intended for research and analytical applications. Bragsin1 is a potent, selective and noncompetitive inhibitor of the ArfGEF BRAG2, inhibits Arf GTPase activation, with an IC50 of 3 μM. Bragsin1 binds to PH domain of BRAG2, and is a noncompetitive interfacial inhibitor. Bragsin1 has no effect on the Sec7 domain of human ArfGEFs. Anti-cancer activity .
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Art. -Nr.: HY-P78740
Reinheit:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MUC1; Mucin Short Variant E1; Prev. PUM; MUC1 Isoform SV7-LSP; Prev. MCKD1; MUC1 Isoform J18; KL-6; MUC1 Isoform J16; PEM; MUC1 Isoform J15; EMA; MUC1 Isoform J24; ADMCKD1; MUC1 Isoform T12; Mucin-1; MUC1 Isoform T13; ADMCKD; MUC1 Isoform M11; Ca15-3; MUC
Species:  
Human
Source:  
HEK293
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