369631-68-5

Bragsin1 Chemical Structure
369631-68-5

Chemical Structure

Bragsin1

  • CAS No.: 369631-68-5
  • Formula:C11H6F3NO4
  • Molecular Weight:273.16

IUPAC Name: 6-methyl-5-nitro-2-(trifluoromethyl)-4H-chromen-4-one

InChIKey: WEUSXIBCGCFOQR-UHFFFAOYSA-N

SMILES: O=C1C=C(C(F)(F)F)OC2=CC=C(C)C([N+]([O-])=O)=C21

Biological Activity: Bragsin1 is a potent, selective and noncompetitive inhibitor of the ArfGEF BRAG2, inhibits Arf GTPase activation, with an IC50 of 3 μM. Bragsin1 binds to PH domain of BRAG2, and is a noncompetitive interfacial inhibitor. Bragsin1 has no effect on the Sec7 domain of human ArfGEFs. Anti-cancer activity[1].

Cat. No. Product Name Purity Description Pricing
HY-111549 		Bragsin1 99.91% Bragsin1 is a potent, selective and noncompetitive inhibitor of the ArfGEF BRAG2, inhibits Arf GTPase activation, with an IC50 of 3 μM. Bragsin1 binds to PH domain of BRAG2, and is a noncompetitive interfacial inhibitor. Bragsin1 has no effect on the Sec7 domain of human ArfGEFs. Anti-cancer activity.
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HY-111549R 		Bragsin1 (Standard) ≥98% Bragsin1 (Standard) is the analytical standard of Bragsin1 (HY-111549). This product is intended for research and analytical applications. Bragsin1 is a potent, selective and noncompetitive inhibitor of the ArfGEF BRAG2, inhibits Arf GTPase activation, with an IC50 of 3 μM. Bragsin1 binds to PH domain of BRAG2, and is a noncompetitive interfacial inhibitor. Bragsin1 has no effect on the Sec7 domain of human ArfGEFs. Anti-cancer activity.
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  • /
loading...
Size Price
Stock Quantity Availability Operate
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In-stock
(Estimated to ship on )
(Estimated to ship TODAY)
Estimated to ship on
(Estimated to ship TODAY)

Amount:

USD 0.00

This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

Pricing 
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Structural Analogs

References

Keywords